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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FECH
All Species:
15.15
Human Site:
S25
Identified Species:
25.64
UniProt:
P22830
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22830
NP_000131.2
423
47862
S25
L
L
R
D
P
L
A
S
S
S
W
R
V
C
Q
Chimpanzee
Pan troglodytes
Q3YA36
423
47946
S25
L
L
R
D
P
L
V
S
S
S
W
R
V
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001085580
422
47841
S18
L
L
R
D
P
L
A
S
S
S
W
R
V
C
Q
Dog
Lupus familis
XP_852936
400
45170
T19
R
C
Q
S
I
G
A
T
A
V
A
A
T
E
T
Cat
Felis silvestris
Mouse
Mus musculus
P22315
420
47112
H25
L
L
R
E
P
L
V
H
G
S
S
R
A
C
Q
Rat
Rattus norvegicus
NP_001101904
422
47533
Y25
L
F
R
E
P
L
V
Y
G
S
S
R
A
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510557
430
49042
A35
S
L
I
K
N
N
V
A
T
H
V
R
A
H
H
Chicken
Gallus gallus
O42479
402
45411
L18
L
V
A
G
G
R
Q
L
R
V
P
L
R
W
R
Frog
Xenopus laevis
O57478
411
46021
S19
G
H
I
L
R
N
E
S
S
A
G
L
V
T
Q
Zebra Danio
Brachydanio rerio
NP_571706
409
46017
P19
Q
L
V
R
C
G
S
P
V
G
L
C
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9S8
384
43579
G18
L
A
S
G
L
A
G
G
V
R
N
L
S
G
Q
Honey Bee
Apis mellifera
XP_393413
397
45521
I20
R
Q
C
T
N
L
S
I
L
S
Y
R
H
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04921
512
56600
N33
P
L
L
P
Q
L
S
N
D
S
Q
R
S
V
V
Baker's Yeast
Sacchar. cerevisiae
P16622
393
44578
T19
F
L
R
R
S
Q
L
T
I
T
R
S
F
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
86
N.A.
88.1
88.8
N.A.
82.7
79.6
78.4
71.8
N.A.
49.1
48.2
N.A.
N.A.
Protein Similarity:
100
99
96.9
89.5
N.A.
92.6
93.1
N.A.
89.3
85.1
85.3
81.8
N.A.
64.7
66.4
N.A.
N.A.
P-Site Identity:
100
86.6
100
6.6
N.A.
60
53.3
N.A.
13.3
6.6
26.6
6.6
N.A.
13.3
20
N.A.
N.A.
P-Site Similarity:
100
86.6
100
26.6
N.A.
66.6
60
N.A.
26.6
20
33.3
20
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.2
45.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
22
8
8
8
8
8
22
0
0
% A
% Cys:
0
8
8
0
8
0
0
0
0
0
0
8
0
29
0
% C
% Asp:
0
0
0
22
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
15
0
0
8
0
0
0
0
0
0
8
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
0
0
15
8
15
8
8
15
8
8
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
0
0
8
8
8
% H
% Ile:
0
0
15
0
8
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
50
58
8
8
8
50
8
8
8
0
8
22
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
15
0
8
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
8
36
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
8
8
8
0
8
8
8
0
0
0
8
0
0
0
50
% Q
% Arg:
15
0
43
15
8
8
0
0
8
8
8
58
8
0
8
% R
% Ser:
8
0
8
8
8
0
22
29
29
50
15
8
15
15
8
% S
% Thr:
0
0
0
8
0
0
0
15
8
8
0
0
8
8
8
% T
% Val:
0
8
8
0
0
0
29
0
15
15
8
0
29
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
22
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _