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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHCGR
All Species:
7.88
Human Site:
S681
Identified Species:
19.26
UniProt:
P22888
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22888
NP_000224.2
699
78643
S681
S
Q
S
T
L
K
L
S
T
L
H
C
Q
G
T
Chimpanzee
Pan troglodytes
XP_525753
695
78196
A675
R
N
G
H
C
S
S
A
P
R
V
T
N
G
S
Rhesus Macaque
Macaca mulatta
XP_001114090
703
78928
S685
S
Q
S
T
L
K
L
S
T
L
H
C
Q
G
T
Dog
Lupus familis
XP_538486
704
78758
S686
S
Q
S
A
L
K
L
S
P
L
Q
C
Q
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
P30730
700
78197
P677
G
F
P
R
S
S
K
P
S
Q
A
A
L
K
L
Rat
Rattus norvegicus
P16235
700
78018
P677
G
F
P
G
A
S
K
P
S
Q
A
T
L
K
L
Wallaby
Macropus eugenll
Q6YNB6
694
78462
M676
R
N
G
Q
C
P
L
M
A
K
S
N
S
G
A
Platypus
Ornith. anatinus
XP_001513769
619
67078
A602
P
S
P
L
G
C
R
A
A
A
P
S
R
E
A
Chicken
Gallus gallus
P79763
693
78680
A675
R
N
G
H
Y
P
T
A
S
K
N
S
D
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_991188
708
78044
M691
S
K
G
P
R
A
V
M
W
M
S
S
F
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.6
96.1
86.2
N.A.
82.8
85
52
52
53.5
N.A.
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.5
97.1
90.4
N.A.
89.4
91
69.1
65.6
68.6
N.A.
69
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
0
0
13.3
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
73.3
N.A.
6.6
6.6
13.3
13.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
0
30
20
10
20
10
0
0
20
% A
% Cys:
0
0
0
0
20
10
0
0
0
0
0
30
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
20
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
20
0
40
10
10
0
0
0
0
0
0
0
0
50
0
% G
% His:
0
0
0
20
0
0
0
0
0
0
20
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
30
20
0
0
20
0
0
0
20
0
% K
% Leu:
0
0
0
10
30
0
40
0
0
30
0
0
20
0
20
% L
% Met:
0
0
0
0
0
0
0
20
0
10
0
0
0
0
0
% M
% Asn:
0
30
0
0
0
0
0
0
0
0
10
10
10
0
0
% N
% Pro:
10
0
30
10
0
20
0
20
20
0
10
0
0
10
0
% P
% Gln:
0
30
0
10
0
0
0
0
0
20
10
0
30
0
10
% Q
% Arg:
30
0
0
10
10
0
10
0
0
10
0
0
10
0
0
% R
% Ser:
40
10
30
0
10
30
10
30
30
0
20
30
10
0
10
% S
% Thr:
0
0
0
20
0
0
10
0
20
0
0
20
0
0
40
% T
% Val:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _