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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROZ All Species: 4.24
Human Site: S89 Identified Species: 11.67
UniProt: P22891 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22891 NP_003882.1 400 44744 S89 W R R Y K G G S P C I S Q P C
Chimpanzee Pan troglodytes Q95ND7 461 51746 D95 W K Q Y V D G D Q C E S N P C
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CQW3 399 44286 S89 W R Q Y G G G S P C V S Q P C
Rat Rattus norvegicus Q63207 482 54247 D88 W N K Y E D G D Q C E S S P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515205 451 50554 R112 M A R Q K R A R S Y V I E E V
Chicken Gallus gallus Q804X6 471 51786 D88 W K I Y I D G D Q C N S N P C
Frog Xenopus laevis NP_001083161 462 52021 D87 W N K Y Y D D D Q C K S N P C
Zebra Danio Brachydanio rerio XP_002660371 404 45069 D100 W A K Y Y D G D Q C R S N P C
Tiger Blowfish Takifugu rubipres NP_001027863 441 49311 N86 W K I Y N R P N S C K S N P C
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.6 N.A. N.A. N.A. 67 29.8 N.A. 43 31 32 34.9 31.5 N.A. N.A. N.A. N.A.
Protein Similarity: 100 44 N.A. N.A. N.A. 80.2 44.8 N.A. 57.2 43 47.4 53.7 47.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 N.A. N.A. N.A. 80 46.6 N.A. 13.3 46.6 40 46.6 40 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 N.A. N.A. N.A. 93.3 60 N.A. 26.6 53.3 46.6 53.3 53.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 0 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 89 0 0 0 0 89 % C
% Asp: 0 0 0 0 0 56 12 56 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 0 0 0 0 0 23 0 12 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 23 67 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 23 0 12 0 0 0 0 0 12 12 0 0 0 % I
% Lys: 0 34 34 0 23 0 0 0 0 0 23 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 0 0 12 0 0 12 0 0 12 0 56 0 0 % N
% Pro: 0 0 0 0 0 0 12 0 23 0 0 0 0 89 0 % P
% Gln: 0 0 23 12 0 0 0 0 56 0 0 0 23 0 0 % Q
% Arg: 0 23 23 0 0 23 0 12 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 23 23 0 0 89 12 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 0 0 0 23 0 0 0 12 % V
% Trp: 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 89 23 0 0 0 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _