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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROZ All Species: 3.94
Human Site: T339 Identified Species: 10.83
UniProt: P22891 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22891 NP_003882.1 400 44744 T339 N V T V T T R T Y C E R S S V
Chimpanzee Pan troglodytes Q95ND7 461 51746 N392 S T K F T I Y N N M F C A G F
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CQW3 399 44286 T338 N V T V T T R T S C E K G S V
Rat Rattus norvegicus Q63207 482 54247 Q398 S T S F S I T Q N M F C A G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515205 451 50554 M389 N G T V T S R M F C V K P S G
Chicken Gallus gallus Q804X6 471 51786 H402 S T S T T I L H S M F C A G Y
Frog Xenopus laevis NP_001083161 462 52021 D391 S S T F A I T D N M F C A G F
Zebra Danio Brachydanio rerio XP_002660371 404 45069 A343 F C M K R E S A G S E R C T V
Tiger Blowfish Takifugu rubipres NP_001027863 441 49311 G366 T Q N M F C A G Y M E G R Q D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.6 N.A. N.A. N.A. 67 29.8 N.A. 43 31 32 34.9 31.5 N.A. N.A. N.A. N.A.
Protein Similarity: 100 44 N.A. N.A. N.A. 80.2 44.8 N.A. 57.2 43 47.4 53.7 47.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. N.A. N.A. 80 0 N.A. 46.6 6.6 6.6 20 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. N.A. N.A. 86.6 26.6 N.A. 66.6 26.6 20 26.6 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 12 12 0 0 0 0 45 0 0 % A
% Cys: 0 12 0 0 0 12 0 0 0 34 0 45 12 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 12 0 0 0 0 45 0 0 0 0 % E
% Phe: 12 0 0 34 12 0 0 0 12 0 45 0 0 0 23 % F
% Gly: 0 12 0 0 0 0 0 12 12 0 0 12 12 45 12 % G
% His: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 12 0 0 0 0 0 0 0 23 0 0 0 % K
% Leu: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % L
% Met: 0 0 12 12 0 0 0 12 0 56 0 0 0 0 0 % M
% Asn: 34 0 12 0 0 0 0 12 34 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % P
% Gln: 0 12 0 0 0 0 0 12 0 0 0 0 0 12 0 % Q
% Arg: 0 0 0 0 12 0 34 0 0 0 0 23 12 0 0 % R
% Ser: 45 12 23 0 12 12 12 0 23 12 0 0 12 34 0 % S
% Thr: 12 34 45 12 56 23 23 23 0 0 0 0 0 12 0 % T
% Val: 0 23 0 34 0 0 0 0 0 0 12 0 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 23 0 0 0 0 0 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _