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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP8
All Species:
14.85
Human Site:
S50
Identified Species:
40.83
UniProt:
P22894
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22894
NP_002415.1
467
53412
S50
L
P
S
N
Q
Y
Q
S
T
R
K
N
G
T
N
Chimpanzee
Pan troglodytes
XP_001153516
467
53426
S50
L
P
S
N
Q
Y
Q
S
T
R
K
N
G
T
N
Rhesus Macaque
Macaca mulatta
XP_001098000
467
53474
S50
L
P
S
N
Q
Y
Q
S
T
R
K
N
G
T
S
Dog
Lupus familis
XP_546547
451
51518
E51
V
I
M
E
K
L
R
E
M
Q
R
F
F
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O70138
465
53062
S52
L
P
S
N
Q
F
R
S
S
R
N
A
T
M
V
Rat
Rattus norvegicus
O88766
466
53258
S53
L
P
S
N
Q
F
R
S
A
R
N
A
T
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509994
629
71900
F50
L
R
N
M
K
W
K
F
M
K
D
G
D
A
V
Chicken
Gallus gallus
XP_417176
466
53780
H51
L
Q
K
D
H
R
P
H
L
R
Q
G
G
K
N
Frog
Xenopus laevis
O13065
467
52794
V51
L
G
T
D
G
G
P
V
G
R
K
K
H
I
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
92
75.5
N.A.
73.2
72.5
N.A.
48.3
55
51.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
94.6
82.6
N.A.
83.5
83.5
N.A.
59.4
71
69.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
46.6
46.6
N.A.
6.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
66.6
60
N.A.
40
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
23
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
0
0
0
0
0
12
0
12
0
0
% D
% Glu:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
23
0
12
0
0
0
12
12
0
0
% F
% Gly:
0
12
0
0
12
12
0
0
12
0
0
23
45
12
0
% G
% His:
0
0
0
0
12
0
0
12
0
0
0
0
12
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
12
% I
% Lys:
0
0
12
0
23
0
12
0
0
12
45
12
0
12
0
% K
% Leu:
89
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% L
% Met:
0
0
12
12
0
0
0
0
23
0
0
0
0
23
0
% M
% Asn:
0
0
12
56
0
0
0
0
0
0
23
34
0
0
34
% N
% Pro:
0
56
0
0
0
0
23
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
56
0
34
0
0
12
12
0
0
0
12
% Q
% Arg:
0
12
0
0
0
12
34
0
0
78
12
0
0
0
0
% R
% Ser:
0
0
56
0
0
0
0
56
12
0
0
0
0
0
12
% S
% Thr:
0
0
12
0
0
0
0
0
34
0
0
0
23
34
0
% T
% Val:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _