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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPA
All Species:
42.12
Human Site:
Y181
Identified Species:
71.28
UniProt:
P23025
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23025
NP_000371.1
273
31368
Y181
Q
W
G
D
M
K
L
Y
L
K
L
Q
I
V
K
Chimpanzee
Pan troglodytes
XP_001156167
264
30052
Y181
Q
W
G
D
M
K
L
Y
L
K
L
Q
I
V
K
Rhesus Macaque
Macaca mulatta
XP_001114093
273
31294
Y181
Q
W
G
D
M
K
L
Y
L
K
L
Q
I
V
K
Dog
Lupus familis
XP_538745
273
31120
Y181
Q
W
G
D
M
K
L
Y
L
K
L
Q
I
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64267
272
31379
Y180
Q
W
G
D
M
K
L
Y
L
K
L
Q
V
V
K
Rat
Rattus norvegicus
NP_001100126
241
27598
R171
F
I
V
K
K
N
P
R
H
S
Q
W
G
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505460
163
18549
D93
Q
Y
L
L
K
D
C
D
L
E
K
R
E
P
V
Chicken
Gallus gallus
P27089
267
30960
Y175
R
W
G
D
M
K
L
Y
L
K
L
Q
V
I
K
Frog
Xenopus laevis
P27088
267
31162
Y175
H
W
G
D
M
K
L
Y
L
K
A
Q
V
I
K
Zebra Danio
Brachydanio rerio
NP_956765
549
61714
Y183
R
W
G
D
M
K
L
Y
L
K
T
Q
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28518
296
33857
Y202
R
W
G
E
M
K
L
Y
L
H
L
Q
I
H
Q
Honey Bee
Apis mellifera
XP_395702
268
31347
Y174
N
W
G
E
M
K
L
Y
L
Q
L
Q
I
E
Q
Nematode Worm
Caenorhab. elegans
NP_492025
241
28884
Y147
R
Y
G
D
M
K
L
Y
L
K
C
Q
I
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28519
371
43020
F268
T
F
A
R
M
Q
L
F
V
R
C
E
V
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
97.4
93.4
N.A.
84.9
73.2
N.A.
42.8
65.9
69.5
31.6
N.A.
41.8
47.6
35.5
N.A.
Protein Similarity:
100
86.8
98.1
95.2
N.A.
93
79.4
N.A.
50.1
81.6
82
39.1
N.A.
61.1
67
55.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
13.3
80
73.3
73.3
N.A.
66.6
66.6
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
33.3
100
86.6
86.6
N.A.
86.6
86.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
0
65
0
8
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
15
0
0
0
0
0
8
0
8
8
29
0
% E
% Phe:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
79
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
50
15
0
% I
% Lys:
0
0
0
8
15
79
0
0
0
65
8
0
0
0
58
% K
% Leu:
0
0
8
8
0
0
86
0
86
0
58
0
0
0
0
% L
% Met:
0
0
0
0
86
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
43
0
0
0
0
8
0
0
0
8
8
79
0
0
15
% Q
% Arg:
29
0
0
8
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
36
36
8
% V
% Trp:
0
72
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _