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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPA
All Species:
23.94
Human Site:
Y257
Identified Species:
40.51
UniProt:
P23025
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23025
NP_000371.1
273
31368
Y257
E
N
L
E
D
D
M
Y
R
K
T
C
T
M
C
Chimpanzee
Pan troglodytes
XP_001156167
264
30052
R247
G
V
D
T
V
E
I
R
H
K
E
L
T
V
Q
Rhesus Macaque
Macaca mulatta
XP_001114093
273
31294
Y257
E
N
L
E
D
D
M
Y
R
K
T
C
T
V
C
Dog
Lupus familis
XP_538745
273
31120
Y257
E
N
L
E
D
D
M
Y
R
K
T
C
T
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q64267
272
31379
Y256
E
N
L
E
D
D
M
Y
R
K
T
C
T
L
C
Rat
Rattus norvegicus
NP_001100126
241
27598
G226
F
D
K
K
V
K
V
G
F
Y
D
A
M
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505460
163
18549
E148
E
A
R
E
G
R
R
E
K
R
E
K
M
K
Q
Chicken
Gallus gallus
P27089
267
30960
Y251
E
N
V
D
E
E
T
Y
K
K
T
C
T
V
C
Frog
Xenopus laevis
P27088
267
31162
Y251
E
H
V
E
E
D
S
Y
K
K
T
C
I
T
C
Zebra Danio
Brachydanio rerio
NP_956765
549
61714
D259
E
L
L
D
E
E
E
D
S
F
S
E
K
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28518
296
33857
D278
D
T
Y
D
E
E
E
D
T
Y
T
H
T
C
I
Honey Bee
Apis mellifera
XP_395702
268
31347
Y252
Y
N
E
D
N
D
T
Y
T
H
S
C
I
T
C
Nematode Worm
Caenorhab. elegans
NP_492025
241
28884
W225
T
H
V
E
E
D
T
W
R
R
T
C
I
T
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28519
371
43020
H337
K
H
G
K
A
H
I
H
H
F
S
D
P
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
97.4
93.4
N.A.
84.9
73.2
N.A.
42.8
65.9
69.5
31.6
N.A.
41.8
47.6
35.5
N.A.
Protein Similarity:
100
86.8
98.1
95.2
N.A.
93
79.4
N.A.
50.1
81.6
82
39.1
N.A.
61.1
67
55.6
N.A.
P-Site Identity:
100
13.3
93.3
93.3
N.A.
93.3
0
N.A.
13.3
53.3
53.3
13.3
N.A.
13.3
33.3
40
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
26.6
93.3
80
40
N.A.
40
53.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
58
0
15
58
% C
% Asp:
8
8
8
29
29
50
0
15
0
0
8
8
0
0
8
% D
% Glu:
58
0
8
50
36
29
15
8
0
0
15
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
8
15
0
0
0
0
0
% F
% Gly:
8
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
22
0
0
0
8
0
8
15
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
0
0
22
0
15
% I
% Lys:
8
0
8
15
0
8
0
0
22
50
0
8
8
15
0
% K
% Leu:
0
8
36
0
0
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
29
0
0
0
0
0
15
8
0
% M
% Asn:
0
43
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
0
0
8
0
0
8
8
8
36
15
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
8
0
22
0
0
0
0
% S
% Thr:
8
8
0
8
0
0
22
0
15
0
58
0
50
22
0
% T
% Val:
0
8
22
0
15
0
8
0
0
0
0
0
0
36
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
50
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _