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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMPD1
All Species:
34.24
Human Site:
Y463
Identified Species:
83.7
UniProt:
P23109
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23109
NP_000027.1
747
86490
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Chimpanzee
Pan troglodytes
XP_513671
747
86428
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Rhesus Macaque
Macaca mulatta
XP_001111615
747
86491
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Dog
Lupus familis
XP_848536
747
86563
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1D3
745
86001
Y461
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Rat
Rattus norvegicus
P10759
747
86413
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506221
708
81695
N429
Y
D
V
F
R
A
K
N
F
L
P
H
F
G
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957187
717
82918
Y434
M
I
Q
V
P
R
I
Y
D
I
F
R
G
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80452
839
95111
Y551
L
I
Q
L
P
R
L
Y
N
I
Y
K
D
M
G
Baker's Yeast
Sacchar. cerevisiae
P15274
810
93283
Y522
L
V
Q
I
P
R
L
Y
D
I
Y
K
K
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
93.8
N.A.
92.5
92.7
N.A.
69.7
N.A.
N.A.
70.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.5
96.7
N.A.
96.2
96.1
N.A.
79.7
N.A.
N.A.
81.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
36.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
56.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
80
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
70
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
80
0
10
0
0
70
0
0
30
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
20
10
60
10
% K
% Leu:
20
0
0
10
0
0
20
0
0
10
0
0
0
0
0
% L
% Met:
70
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
70
% N
% Pro:
0
0
0
0
90
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
90
0
0
0
0
0
70
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
10
10
70
0
0
0
0
0
60
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
90
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _