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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBLN1 All Species: 20.3
Human Site: S447 Identified Species: 44.67
UniProt: P23142 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23142 NP_001987.2 703 77214 S447 E D I N E C S S S P C S Q E C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109966 706 77336 Q447 E G L S Q C A Q L S C V S Y C
Dog Lupus familis XP_531698 695 76428 S439 E D V N E C S S S P C S Q E C
Cat Felis silvestris
Mouse Mus musculus Q08879 705 78014 N449 E D V N E C L N S P C S Q E C
Rat Rattus norvegicus Q9WVH8 448 50142 V208 D G R S C Q D V N E C E T E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511339 689 76020 S434 E D L N E C D S S P C S Q E C
Chicken Gallus gallus O73775 704 78120 S448 E D L N E C E S S P C S Q E C
Frog Xenopus laevis NP_001089430 693 76573 N438 D D V D E C S N N P C S Q E C
Zebra Danio Brachydanio rerio O42182 681 74442 S422 D D V N E C E S S P C S Q G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O77469 728 79302 T480 E D V N E C T T G I A A C E Q
Sea Urchin Strong. purpuratus XP_787649 633 69758 Y393 C I N Q E G G Y V C Q C P A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.4 87.9 N.A. 84.9 24.7 N.A. 72.2 73.1 68.2 56.7 N.A. N.A. N.A. 33.6 28.8
Protein Similarity: 100 N.A. 94.3 92.3 N.A. 92.1 36.4 N.A. 83.2 85 82.2 71.1 N.A. N.A. N.A. 49.8 43.2
P-Site Identity: 100 N.A. 26.6 93.3 N.A. 80 13.3 N.A. 86.6 86.6 66.6 73.3 N.A. N.A. N.A. 40 6.6
P-Site Similarity: 100 N.A. 53.3 100 N.A. 93.3 33.3 N.A. 93.3 93.3 100 86.6 N.A. N.A. N.A. 66.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 10 0 10 0 % A
% Cys: 10 0 0 0 10 82 0 0 0 10 82 10 10 0 73 % C
% Asp: 28 73 0 10 0 0 19 0 0 0 0 0 0 0 0 % D
% Glu: 64 0 0 0 82 0 19 0 0 10 0 10 0 73 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 10 10 0 10 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 28 0 0 0 10 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 64 0 0 0 19 19 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 64 0 0 10 0 0 % P
% Gln: 0 0 0 10 10 10 0 10 0 0 10 0 64 0 10 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 19 0 0 28 46 55 10 0 64 10 0 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 0 0 10 0 0 % T
% Val: 0 0 46 0 0 0 0 10 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _