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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA6
All Species:
27.88
Human Site:
T889
Identified Species:
51.11
UniProt:
P23229
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23229
NP_000201.2
1130
126633
T889
L
T
N
L
G
T
A
T
L
N
I
Q
W
P
K
Chimpanzee
Pan troglodytes
XP_515909
1306
145305
T1065
L
T
N
L
G
T
A
T
L
N
I
Q
W
P
K
Rhesus Macaque
Macaca mulatta
XP_001086200
1361
150353
T1120
L
K
N
L
G
T
A
T
L
N
I
Q
W
P
K
Dog
Lupus familis
XP_535964
1130
126485
T889
L
K
N
L
G
T
A
T
L
N
I
Q
W
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61739
1091
122129
T850
L
K
N
L
G
T
A
T
L
N
I
Q
W
P
K
Rat
Rattus norvegicus
Q63258
1135
124176
K890
E
G
G
Q
G
P
E
K
K
G
I
C
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514660
1090
122201
F850
L
R
N
L
G
T
A
F
L
N
I
Q
W
P
K
Chicken
Gallus gallus
P26007
1072
119182
S849
L
K
T
F
G
T
A
S
L
D
I
Q
W
P
K
Frog
Xenopus laevis
Q06274
1050
115944
G833
G
P
S
S
I
S
Q
G
I
L
E
L
R
C
P
Zebra Danio
Brachydanio rerio
NP_001138253
1092
121705
S849
L
K
S
F
G
T
A
S
L
N
I
Q
W
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24247
1146
127955
P907
A
S
G
S
R
E
N
P
A
Y
L
S
A
P
A
Honey Bee
Apis mellifera
XP_625120
1093
122912
S863
E
I
P
I
V
Q
A
S
G
D
G
E
C
I
L
Nematode Worm
Caenorhab. elegans
Q03600
1139
127749
T895
L
L
D
V
P
T
I
T
T
E
F
T
D
G
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
78.6
92.6
N.A.
89.3
48.1
N.A.
78.1
67.6
27.7
60.7
N.A.
28
32.7
22
N.A.
Protein Similarity:
100
86.4
79.5
96.6
N.A.
93.1
67.4
N.A.
87.2
80.1
45.1
75.4
N.A.
47.7
51.2
40.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
86.6
66.6
0
73.3
N.A.
6.6
6.6
20
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
26.6
N.A.
86.6
80
20
86.6
N.A.
20
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
70
0
8
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
16
0
0
8
0
0
% D
% Glu:
16
0
0
0
0
8
8
0
0
8
8
8
0
0
0
% E
% Phe:
0
0
0
16
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
8
8
16
0
70
0
0
8
8
8
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
8
0
8
0
8
0
70
0
0
8
0
% I
% Lys:
0
39
0
0
0
0
0
8
8
0
0
0
0
0
62
% K
% Leu:
70
8
0
47
0
0
0
0
62
8
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
47
0
0
0
8
0
0
54
0
0
0
0
0
% N
% Pro:
0
8
8
0
8
8
0
8
0
0
0
0
0
77
8
% P
% Gln:
0
0
0
8
0
8
8
0
0
0
0
62
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
0
8
16
16
0
8
0
24
0
0
0
8
8
0
0
% S
% Thr:
0
16
8
0
0
70
0
47
8
0
0
8
0
0
8
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
62
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _