KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBG1
All Species:
53.94
Human Site:
S336
Identified Species:
79.11
UniProt:
P23258
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23258
NP_001061.2
451
51170
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Chimpanzee
Pan troglodytes
XP_001162175
464
52570
S349
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548085
451
51005
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK3
451
51103
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Rat
Rattus norvegicus
P83888
451
51082
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418146
427
48240
I325
E
R
K
L
A
N
F
I
P
W
G
P
A
S
I
Frog
Xenopus laevis
P23330
451
51149
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Zebra Danio
Brachydanio rerio
NP_957202
451
51078
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23257
475
53321
S341
D
P
T
Q
V
H
K
S
L
Q
R
I
R
D
R
Honey Bee
Apis mellifera
XP_394981
453
51413
S336
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Nematode Worm
Caenorhab. elegans
P34475
444
49910
E336
A
H
T
I
M
T
A
E
Q
N
V
D
F
A
I
Sea Urchin
Strong. purpuratus
NP_999657
460
51977
S339
D
P
T
Q
V
H
K
S
L
Q
R
I
R
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41808
469
52822
S338
D
P
T
Q
V
H
E
S
L
Q
R
I
R
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38558
474
53259
S338
D
P
T
Q
V
H
E
S
L
Q
R
I
R
E
R
Baker's Yeast
Sacchar. cerevisiae
P53378
473
52609
A334
E
P
R
Q
I
S
R
A
M
T
K
L
Q
Q
R
Red Bread Mold
Neurospora crassa
P53377
461
51580
S336
D
P
T
D
V
H
K
S
L
L
R
I
R
E
R
Conservation
Percent
Protein Identity:
100
97.1
N.A.
98.2
N.A.
96.9
98.8
N.A.
N.A.
92.2
98.2
98
N.A.
75.3
83.6
43.9
84.1
Protein Similarity:
100
97.1
N.A.
99.7
N.A.
98.2
99.5
N.A.
N.A.
93.3
99.3
99.3
N.A.
85.6
93.3
64.9
93
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
0
100
100
N.A.
93.3
100
6.6
100
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
13.3
100
100
N.A.
100
100
13.3
100
Percent
Protein Identity:
N.A.
72
N.A.
72.1
38.9
66.1
Protein Similarity:
N.A.
83.1
N.A.
82.7
59.8
80.6
P-Site Identity:
N.A.
93.3
N.A.
93.3
20
86.6
P-Site Similarity:
N.A.
100
N.A.
100
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
7
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
7
0
0
0
0
0
0
0
7
0
7
0
% D
% Glu:
13
0
0
0
0
0
13
7
0
0
0
0
0
75
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
7
0
0
0
82
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
7
0
0
0
82
0
0
13
% I
% Lys:
0
0
7
0
0
0
69
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
82
7
0
7
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
88
0
0
0
0
0
0
7
0
0
7
0
0
0
% P
% Gln:
0
0
0
82
0
0
0
0
7
75
0
0
7
7
0
% Q
% Arg:
0
7
7
0
0
0
7
0
0
0
82
0
82
0
88
% R
% Ser:
0
0
0
0
0
7
0
82
0
0
0
0
0
7
0
% S
% Thr:
0
0
88
0
0
7
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
82
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _