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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBG1 All Species: 47.58
Human Site: S369 Identified Species: 69.78
UniProt: P23258 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23258 NP_001061.2 451 51170 S369 R K S P Y L P S A H R V S G L
Chimpanzee Pan troglodytes XP_001162175 464 52570 S382 R K S P Y L P S A H R V S G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548085 451 51005 S369 R K S P Y L P S A H R V S G L
Cat Felis silvestris
Mouse Mus musculus Q8VCK3 451 51103 S369 R K S P Y L P S A H R V S G L
Rat Rattus norvegicus P83888 451 51082 S369 R K S P Y L P S A H R V S G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418146 427 48240 M354 H R V S G L M M A N H T N I S
Frog Xenopus laevis P23330 451 51149 S369 R K S P Y L P S A H R V S G L
Zebra Danio Brachydanio rerio NP_957202 451 51078 S369 R R S P Y L P S A H R V S G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23257 475 53321 S374 R S S P Y V Q S N H R V S G L
Honey Bee Apis mellifera XP_394981 453 51413 T369 R K S P Y I Q T A H R V S G L
Nematode Worm Caenorhab. elegans P34475 444 49910 P367 P L S P Y V R P Q Y K V S G L
Sea Urchin Strong. purpuratus NP_999657 460 51977 T372 K K S P Y V Q T A H R V S G L
Poplar Tree Populus trichocarpa
Maize Zea mays Q41808 469 52822 T371 R K S P Y V Q T T H R V S G L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38558 474 53259 T371 K K S P Y V Q T S H R V S G L
Baker's Yeast Sacchar. cerevisiae P53378 473 52609 N368 P Y L P L Q P N E N E V S G M
Red Bread Mold Neurospora crassa P53377 461 51580 M369 K R S P Y V T M A H R V S G L
Conservation
Percent
Protein Identity: 100 97.1 N.A. 98.2 N.A. 96.9 98.8 N.A. N.A. 92.2 98.2 98 N.A. 75.3 83.6 43.9 84.1
Protein Similarity: 100 97.1 N.A. 99.7 N.A. 98.2 99.5 N.A. N.A. 93.3 99.3 99.3 N.A. 85.6 93.3 64.9 93
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 13.3 100 93.3 N.A. 73.3 80 46.6 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 33.3 100 100 N.A. 80 93.3 66.6 93.3
Percent
Protein Identity: N.A. 72 N.A. 72.1 38.9 66.1
Protein Similarity: N.A. 83.1 N.A. 82.7 59.8 80.6
P-Site Identity: N.A. 73.3 N.A. 66.6 33.3 66.6
P-Site Similarity: N.A. 86.6 N.A. 93.3 53.3 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 69 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 0 0 94 0 % G
% His: 7 0 0 0 0 0 0 0 0 82 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % I
% Lys: 19 63 0 0 0 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 7 7 0 7 50 0 0 0 0 0 0 0 0 88 % L
% Met: 0 0 0 0 0 0 7 13 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 7 7 13 0 0 7 0 0 % N
% Pro: 13 0 0 94 0 0 50 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 32 0 7 0 0 0 0 0 0 % Q
% Arg: 63 19 0 0 0 0 7 0 0 0 82 0 0 0 0 % R
% Ser: 0 7 88 7 0 0 0 50 7 0 0 0 94 0 7 % S
% Thr: 0 0 0 0 0 0 7 25 7 0 0 7 0 0 0 % T
% Val: 0 0 7 0 0 38 0 0 0 0 0 94 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 88 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _