KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBG1
All Species:
49.7
Human Site:
S424
Identified Species:
72.89
UniProt:
P23258
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23258
NP_001061.2
451
51170
S424
N
F
D
E
M
D
T
S
R
E
I
V
Q
Q
L
Chimpanzee
Pan troglodytes
XP_001162175
464
52570
S437
N
F
D
E
M
D
T
S
R
E
I
V
Q
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548085
451
51005
S424
N
F
D
E
L
D
T
S
R
E
V
V
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK3
451
51103
S424
N
F
E
E
M
H
R
S
R
E
V
V
Q
E
L
Rat
Rattus norvegicus
P83888
451
51082
S424
N
F
D
E
M
D
T
S
R
E
I
V
Q
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418146
427
48240
S400
N
F
D
E
L
D
N
S
R
E
I
V
Q
Q
L
Frog
Xenopus laevis
P23330
451
51149
S424
N
F
D
E
L
D
N
S
R
E
I
V
Q
Q
L
Zebra Danio
Brachydanio rerio
NP_957202
451
51078
S424
N
F
D
E
L
D
N
S
R
E
V
V
Q
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23257
475
53321
S429
D
L
N
E
L
D
E
S
R
E
T
V
D
C
L
Honey Bee
Apis mellifera
XP_394981
453
51413
S424
N
L
N
E
L
D
N
S
R
E
V
V
E
Y
L
Nematode Worm
Caenorhab. elegans
P34475
444
49910
F412
K
F
E
K
I
D
N
F
S
L
D
M
M
D
D
Sea Urchin
Strong. purpuratus
NP_999657
460
51977
S427
N
L
D
E
L
D
D
S
R
E
V
V
Q
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41808
469
52822
S427
D
L
S
E
F
D
E
S
R
E
I
I
E
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38558
474
53259
S427
D
L
S
E
F
D
E
S
R
D
I
I
E
S
L
Baker's Yeast
Sacchar. cerevisiae
P53378
473
52609
S426
V
Q
D
E
F
A
E
S
R
E
V
V
Q
S
L
Red Bread Mold
Neurospora crassa
P53377
461
51580
A424
N
L
N
E
F
D
E
A
R
E
V
V
M
D
L
Conservation
Percent
Protein Identity:
100
97.1
N.A.
98.2
N.A.
96.9
98.8
N.A.
N.A.
92.2
98.2
98
N.A.
75.3
83.6
43.9
84.1
Protein Similarity:
100
97.1
N.A.
99.7
N.A.
98.2
99.5
N.A.
N.A.
93.3
99.3
99.3
N.A.
85.6
93.3
64.9
93
P-Site Identity:
100
100
N.A.
80
N.A.
66.6
100
N.A.
N.A.
86.6
86.6
80
N.A.
46.6
53.3
13.3
73.3
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
66.6
80
40
86.6
Percent
Protein Identity:
N.A.
72
N.A.
72.1
38.9
66.1
Protein Similarity:
N.A.
83.1
N.A.
82.7
59.8
80.6
P-Site Identity:
N.A.
46.6
N.A.
40
53.3
46.6
P-Site Similarity:
N.A.
66.6
N.A.
66.6
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
19
0
57
0
0
88
7
0
0
7
7
0
7
13
7
% D
% Glu:
0
0
13
94
0
0
32
0
0
88
0
0
19
13
0
% E
% Phe:
0
57
0
0
25
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
44
13
0
0
0
% I
% Lys:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
38
0
0
44
0
0
0
0
7
0
0
0
0
94
% L
% Met:
0
0
0
0
25
0
0
0
0
0
0
7
13
0
0
% M
% Asn:
69
0
19
0
0
0
32
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
63
44
0
% Q
% Arg:
0
0
0
0
0
0
7
0
94
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
0
0
88
7
0
0
0
0
19
0
% S
% Thr:
0
0
0
0
0
0
25
0
0
0
7
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
44
82
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _