KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KEL
All Species:
3.64
Human Site:
S272
Identified Species:
10
UniProt:
P23276
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23276
NP_000411.1
732
82824
S272
P
S
K
V
Q
E
H
S
S
L
S
I
S
I
T
Chimpanzee
Pan troglodytes
XP_519445
663
75016
Y239
Q
D
Q
E
Q
K
I
Y
A
Q
I
F
R
E
Y
Rhesus Macaque
Macaca mulatta
XP_001091797
857
97238
A395
P
N
K
V
Q
E
H
A
F
R
S
L
I
I
T
Dog
Lupus familis
XP_539859
713
80467
H265
S
I
T
S
Q
L
F
H
F
V
K
P
L
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQF2
713
80847
Q265
V
F
T
S
R
L
F
Q
F
L
R
P
Q
Q
Q
Rat
Rattus norvegicus
P42893
762
86107
S291
L
G
G
G
D
E
D
S
I
R
P
Q
M
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416529
776
89156
F317
Q
D
G
P
P
H
S
F
S
L
T
L
S
F
I
Frog
Xenopus laevis
NP_001080378
766
87192
M300
E
N
S
T
R
E
Q
M
Q
E
I
L
D
F
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16796
848
97043
S370
G
N
L
T
R
S
E
S
E
M
N
A
D
I
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
75.7
76.6
N.A.
72.4
30.9
N.A.
N.A.
35.7
30
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
Protein Similarity:
100
82.3
78.5
84
N.A.
83.6
49.7
N.A.
N.A.
54.9
50.6
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
100
6.6
60
6.6
N.A.
6.6
13.3
N.A.
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
80
13.3
N.A.
13.3
13.3
N.A.
N.A.
33.3
26.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
12
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
0
0
12
0
12
0
0
0
0
0
23
0
0
% D
% Glu:
12
0
0
12
0
45
12
0
12
12
0
0
0
23
23
% E
% Phe:
0
12
0
0
0
0
23
12
34
0
0
12
0
23
0
% F
% Gly:
12
12
23
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
23
12
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
0
12
0
23
12
12
34
12
% I
% Lys:
0
0
23
0
0
12
0
0
0
0
12
0
0
0
0
% K
% Leu:
12
0
12
0
0
23
0
0
0
34
0
34
12
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
12
0
0
12
0
0
% M
% Asn:
0
34
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
23
0
0
12
12
0
0
0
0
0
12
23
0
0
0
% P
% Gln:
23
0
12
0
45
0
12
12
12
12
0
12
12
23
34
% Q
% Arg:
0
0
0
0
34
0
0
0
0
23
12
0
12
0
0
% R
% Ser:
12
12
12
23
0
12
12
34
23
0
23
0
23
0
0
% S
% Thr:
0
0
23
23
0
0
0
0
0
0
12
0
0
0
23
% T
% Val:
12
0
0
23
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _