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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CA6 All Species: 7.27
Human Site: S48 Identified Species: 17.78
UniProt: P23280 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23280 NP_001206.2 308 35367 S48 A C G G Q R Q S P I N L Q R T
Chimpanzee Pan troglodytes XP_528593 453 49094 P157 C A G R F Q S P V D I R P Q L
Rhesus Macaque Macaca mulatta P00916 261 28918 D9 A S P D W G Y D D K N G P E Q
Dog Lupus familis XP_540298 337 37590 S47 E C G S N A Q S P I D I Q T D
Cat Felis silvestris
Mouse Mus musculus P18761 317 36330 S47 S C G G E R Q S P I D V K T E
Rat Rattus norvegicus P27139 260 29095 S8 M S H H W G Y S K S N G P E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505491 247 28064
Chicken Gallus gallus P07630 260 28989 D8 M S H H W G Y D S H N G P A H
Frog Xenopus laevis NP_001085550 525 59625 P53 C A A K H Q S P I D I Q R K K
Zebra Danio Brachydanio rerio Q92051 260 28659 G8 M A H A W G Y G P A D G P E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.7 28.5 33.8 N.A. 51.4 28.8 N.A. 45.7 32.4 33.9 31.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.6 46 51.6 N.A. 68.4 47.4 N.A. 54.2 48.3 42 50.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 46.6 N.A. 53.3 13.3 N.A. 0 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 13.3 60 N.A. 86.6 13.3 N.A. 0 6.6 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 30 10 10 0 10 0 0 0 10 0 0 0 10 0 % A
% Cys: 20 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 20 10 20 30 0 0 0 10 % D
% Glu: 10 0 0 0 10 0 0 0 0 0 0 0 0 30 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 40 20 0 40 0 10 0 0 0 40 0 0 0 % G
% His: 0 0 30 20 10 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 10 30 20 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 10 0 0 10 10 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % L
% Met: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 40 0 0 0 10 % N
% Pro: 0 0 10 0 0 0 0 20 40 0 0 0 50 0 0 % P
% Gln: 0 0 0 0 10 20 30 0 0 0 0 10 20 10 10 % Q
% Arg: 0 0 0 10 0 20 0 0 0 0 0 10 10 10 0 % R
% Ser: 10 30 0 10 0 0 20 40 10 10 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 10 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _