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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA6
All Species:
18.18
Human Site:
T221
Identified Species:
44.44
UniProt:
P23280
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23280
NP_001206.2
308
35367
T221
T
Y
H
G
S
L
T
T
P
P
C
T
E
N
V
Chimpanzee
Pan troglodytes
XP_528593
453
49094
T327
Q
Y
E
G
S
L
T
T
P
P
C
A
Q
G
V
Rhesus Macaque
Macaca mulatta
P00916
261
28918
A175
I
K
T
K
G
K
R
A
P
F
T
N
F
D
P
Dog
Lupus familis
XP_540298
337
37590
T219
R
Y
N
G
S
L
T
T
P
P
C
Y
Q
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P18761
317
36330
T220
T
Y
P
G
S
L
T
T
P
P
C
T
E
N
V
Rat
Rattus norvegicus
P27139
260
29095
A174
K
T
K
G
K
R
A
A
F
A
N
F
D
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505491
247
28064
T161
C
S
E
S
V
I
W
T
I
F
D
A
P
I
T
Chicken
Gallus gallus
P07630
260
28989
S174
Q
T
K
G
K
Q
A
S
F
T
N
F
D
P
T
Frog
Xenopus laevis
NP_001085550
525
59625
T226
R
Y
D
G
S
L
T
T
P
P
C
T
E
N
V
Zebra Danio
Brachydanio rerio
Q92051
260
28659
T174
K
S
K
G
R
Q
T
T
F
A
N
F
D
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
28.5
33.8
N.A.
51.4
28.8
N.A.
45.7
32.4
33.9
31.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.6
46
51.6
N.A.
68.4
47.4
N.A.
54.2
48.3
42
50.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
6.6
66.6
N.A.
93.3
6.6
N.A.
6.6
6.6
86.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
13.3
86.6
N.A.
93.3
13.3
N.A.
13.3
20
86.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
20
0
20
0
20
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
50
0
0
0
10
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
10
0
30
10
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
0
0
30
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
30
20
0
30
10
0
0
% F
% Gly:
0
0
0
80
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% I
% Lys:
20
10
30
10
20
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
30
10
0
30
0
% N
% Pro:
0
0
10
0
0
0
0
0
60
50
0
0
10
30
10
% P
% Gln:
20
0
0
0
0
20
0
0
0
0
0
0
20
0
0
% Q
% Arg:
20
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
10
50
0
0
10
0
0
0
0
0
10
0
% S
% Thr:
20
20
10
0
0
0
60
70
0
10
10
30
0
0
20
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _