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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIB All Species: 57.58
Human Site: S150 Identified Species: 84.44
UniProt: P23284 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23284 NP_000933.1 216 23743 S150 A G K D T N G S Q F F I T T V
Chimpanzee Pan troglodytes XP_001174161 216 23752 S150 A G K D T N G S Q F F I T T V
Rhesus Macaque Macaca mulatta XP_001106524 170 18582 R134 L E G M E V V R K V E S T K T
Dog Lupus familis XP_852389 216 23757 S150 A G K D T N G S Q F F I T T V
Cat Felis silvestris
Mouse Mus musculus P24369 216 23695 S150 A G K D T N G S Q F F I T T V
Rat Rattus norvegicus P24368 216 23784 S150 A G K D T N G S Q F F I T T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508975 216 23586 S150 A G K D T N G S Q F F I T T V
Chicken Gallus gallus P24367 207 22394 S141 A G K D T N G S Q F F I T T V
Frog Xenopus laevis NP_001080505 216 23841 S150 A G K D T N G S Q F F I T T V
Zebra Danio Brachydanio rerio NP_998184 216 23910 S150 A G K D T N G S Q F F I T T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 S173 A G A N T N G S Q F F I C T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52013 204 21909 P145 F I T T V K T P W L D G R H V
Sea Urchin Strong. purpuratus XP_780268 211 22854 S143 A G K D T N G S Q F F L T T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASS6 259 28288 S199 A G P N T N G S Q F F I C T I
Baker's Yeast Sacchar. cerevisiae P35176 225 25308 S141 R G K N T N G S Q F F I T T V
Red Bread Mold Neurospora crassa Q7S7Z6 285 30725 S141 A G K D T N G S Q F F I T T V
Conservation
Percent
Protein Identity: 100 99.5 78.2 95.8 N.A. 93.9 93.5 N.A. 89.3 82.8 86.5 81 N.A. 49.3 N.A. 63.4 65.7
Protein Similarity: 100 99.5 78.6 97.6 N.A. 96.7 96.3 N.A. 93.9 88.8 93 89.8 N.A. 65.1 N.A. 75.9 78.7
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 N.A. 6.6 86.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 N.A. 6.6 100
Percent
Protein Identity: N.A. N.A. N.A. 48.2 50.2 50.1
Protein Similarity: N.A. N.A. N.A. 64.8 65.7 61.4
P-Site Identity: N.A. N.A. N.A. 73.3 86.6 100
P-Site Similarity: N.A. N.A. N.A. 86.6 93.3 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % C
% Asp: 0 0 0 69 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 7 0 0 7 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 88 88 0 0 0 0 % F
% Gly: 0 88 7 0 0 0 88 0 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 82 0 0 13 % I
% Lys: 0 0 75 0 0 7 0 0 7 0 0 0 0 7 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 0 88 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 0 0 88 0 0 0 7 0 0 0 % S
% Thr: 0 0 7 7 88 0 7 0 0 0 0 0 82 88 7 % T
% Val: 0 0 0 0 7 7 7 0 0 7 0 0 0 0 82 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _