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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIB All Species: 52.42
Human Site: T108 Identified Species: 76.89
UniProt: P23284 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23284 NP_000933.1 216 23743 T108 M I Q G G D F T R G D G T G G
Chimpanzee Pan troglodytes XP_001174161 216 23752 T108 M I Q G G D F T R G D G T G G
Rhesus Macaque Macaca mulatta XP_001106524 170 18582 V92 K H Y G P G W V S M A N A G K
Dog Lupus familis XP_852389 216 23757 T108 M I Q G G D F T R G D G T G G
Cat Felis silvestris
Mouse Mus musculus P24369 216 23695 T108 M I Q G G D F T R G D G T G G
Rat Rattus norvegicus P24368 216 23784 T108 M I Q G G D F T R G D G T G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508975 216 23586 T108 M I Q G G D F T R G D G T G G
Chicken Gallus gallus P24367 207 22394 T99 M I Q G G D F T R G D G T G G
Frog Xenopus laevis NP_001080505 216 23841 T108 M I Q G G D F T R G D G T G G
Zebra Danio Brachydanio rerio NP_998184 216 23910 T108 M I Q G G D F T R G D G T G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 T131 M C Q G G D F T N H N G T G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52013 204 21909 I103 D G T G G R S I Y G E K F A D
Sea Urchin Strong. purpuratus XP_780268 211 22854 T101 M I Q G G D F T K G D G T G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASS6 259 28288 E157 M I Q G G D F E K G N G T G G
Baker's Yeast Sacchar. cerevisiae P35176 225 25308 T99 M I Q G G D F T H R S G I G G
Red Bread Mold Neurospora crassa Q7S7Z6 285 30725 T99 M I Q G G D F T K G D G T G G
Conservation
Percent
Protein Identity: 100 99.5 78.2 95.8 N.A. 93.9 93.5 N.A. 89.3 82.8 86.5 81 N.A. 49.3 N.A. 63.4 65.7
Protein Similarity: 100 99.5 78.6 97.6 N.A. 96.7 96.3 N.A. 93.9 88.8 93 89.8 N.A. 65.1 N.A. 75.9 78.7
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 N.A. 20 93.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 N.A. 26.6 100
Percent
Protein Identity: N.A. N.A. N.A. 48.2 50.2 50.1
Protein Similarity: N.A. N.A. N.A. 64.8 65.7 61.4
P-Site Identity: N.A. N.A. N.A. 80 73.3 93.3
P-Site Similarity: N.A. N.A. N.A. 93.3 73.3 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 7 0 7 7 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 88 0 0 0 0 69 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 88 0 0 0 0 0 7 0 0 % F
% Gly: 0 7 0 100 94 7 0 0 0 82 0 88 0 94 88 % G
% His: 0 7 0 0 0 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 0 82 0 0 0 0 0 7 0 0 0 0 7 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 19 0 0 7 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 88 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 13 7 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 88 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 7 0 0 57 7 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 7 0 7 0 7 0 0 0 0 % S
% Thr: 0 0 7 0 0 0 0 82 0 0 0 0 82 0 0 % T
% Val: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _