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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIB
All Species:
48.18
Human Site:
T185
Identified Species:
70.67
UniProt:
P23284
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23284
NP_000933.1
216
23743
T185
V
V
R
K
V
E
S
T
K
T
D
S
R
D
K
Chimpanzee
Pan troglodytes
XP_001174161
216
23752
T185
V
V
R
K
V
E
S
T
K
T
D
S
R
D
K
Rhesus Macaque
Macaca mulatta
XP_001106524
170
18582
I159
I
I
A
D
C
G
K
I
E
V
E
K
P
F
A
Dog
Lupus familis
XP_852389
216
23757
T185
V
V
R
K
V
E
S
T
K
T
D
S
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P24369
216
23695
T185
V
V
R
K
V
E
S
T
K
T
D
S
R
D
K
Rat
Rattus norvegicus
P24368
216
23784
T185
V
V
R
K
V
E
N
T
K
T
D
S
R
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508975
216
23586
T185
V
V
R
K
V
E
S
T
K
T
D
G
R
D
K
Chicken
Gallus gallus
P24367
207
22394
T176
V
V
R
K
V
E
N
T
K
T
D
S
R
D
K
Frog
Xenopus laevis
NP_001080505
216
23841
T185
I
V
R
K
I
E
S
T
K
T
D
G
R
D
K
Zebra Danio
Brachydanio rerio
NP_998184
216
23910
T185
V
V
R
K
I
E
A
T
K
T
D
G
R
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25007
227
24648
Y208
V
V
K
K
I
E
S
Y
G
S
Q
S
G
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52013
204
21909
T170
V
V
R
K
I
E
Q
T
E
K
L
P
G
D
R
Sea Urchin
Strong. purpuratus
XP_780268
211
22854
T178
V
V
R
K
I
E
S
T
K
T
G
R
N
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASS6
259
28288
Q234
V
V
K
L
I
E
E
Q
E
T
D
R
G
D
R
Baker's Yeast
Sacchar. cerevisiae
P35176
225
25308
V176
V
V
H
Y
I
E
N
V
K
T
D
S
R
N
M
Red Bread Mold
Neurospora crassa
Q7S7Z6
285
30725
T176
V
V
E
K
I
E
N
T
K
T
G
P
R
D
A
Conservation
Percent
Protein Identity:
100
99.5
78.2
95.8
N.A.
93.9
93.5
N.A.
89.3
82.8
86.5
81
N.A.
49.3
N.A.
63.4
65.7
Protein Similarity:
100
99.5
78.6
97.6
N.A.
96.7
96.3
N.A.
93.9
88.8
93
89.8
N.A.
65.1
N.A.
75.9
78.7
P-Site Identity:
100
100
0
100
N.A.
100
93.3
N.A.
93.3
93.3
80
80
N.A.
40
N.A.
46.6
73.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
60
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
50.2
50.1
Protein Similarity:
N.A.
N.A.
N.A.
64.8
65.7
61.4
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
69
0
0
82
0
% D
% Glu:
0
0
7
0
0
94
7
0
19
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
7
0
0
7
0
13
19
19
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
7
0
0
50
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
82
0
0
7
0
75
7
0
7
0
7
63
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
25
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
7
0
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% Q
% Arg:
0
0
69
0
0
0
0
0
0
0
0
13
69
0
13
% R
% Ser:
0
0
0
0
0
0
50
0
0
7
0
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
82
0
0
0
0
7
% T
% Val:
88
94
0
0
44
0
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _