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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIB All Species: 50
Human Site: T187 Identified Species: 73.33
UniProt: P23284 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23284 NP_000933.1 216 23743 T187 R K V E S T K T D S R D K P L
Chimpanzee Pan troglodytes XP_001174161 216 23752 T187 R K V E S T K T D S R D K P L
Rhesus Macaque Macaca mulatta XP_001106524 170 18582 V161 A D C G K I E V E K P F A I A
Dog Lupus familis XP_852389 216 23757 T187 R K V E S T K T D S R D K P L
Cat Felis silvestris
Mouse Mus musculus P24369 216 23695 T187 R K V E S T K T D S R D K P L
Rat Rattus norvegicus P24368 216 23784 T187 R K V E N T K T D S R D K P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508975 216 23586 T187 R K V E S T K T D G R D K P L
Chicken Gallus gallus P24367 207 22394 T178 R K V E N T K T D S R D K P L
Frog Xenopus laevis NP_001080505 216 23841 T187 R K I E S T K T D G R D K P L
Zebra Danio Brachydanio rerio NP_998184 216 23910 T187 R K I E A T K T D G R D K P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 S210 K K I E S Y G S Q S G K T S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52013 204 21909 K172 R K I E Q T E K L P G D R P K
Sea Urchin Strong. purpuratus XP_780268 211 22854 T180 R K I E S T K T G R N D K P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASS6 259 28288 T236 K L I E E Q E T D R G D R P R
Baker's Yeast Sacchar. cerevisiae P35176 225 25308 T178 H Y I E N V K T D S R N M P V
Red Bread Mold Neurospora crassa Q7S7Z6 285 30725 T178 E K I E N T K T G P R D A P A
Conservation
Percent
Protein Identity: 100 99.5 78.2 95.8 N.A. 93.9 93.5 N.A. 89.3 82.8 86.5 81 N.A. 49.3 N.A. 63.4 65.7
Protein Similarity: 100 99.5 78.6 97.6 N.A. 96.7 96.3 N.A. 93.9 88.8 93 89.8 N.A. 65.1 N.A. 75.9 78.7
P-Site Identity: 100 100 0 100 N.A. 100 93.3 N.A. 93.3 93.3 86.6 80 N.A. 26.6 N.A. 40 66.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 93.3 100 93.3 93.3 N.A. 46.6 N.A. 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. 48.2 50.2 50.1
Protein Similarity: N.A. N.A. N.A. 64.8 65.7 61.4
P-Site Identity: N.A. N.A. N.A. 33.3 46.6 53.3
P-Site Similarity: N.A. N.A. N.A. 60 73.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 0 0 0 0 0 0 13 0 19 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 69 0 0 82 0 0 0 % D
% Glu: 7 0 0 94 7 0 19 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 7 0 0 7 0 13 19 19 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 50 0 0 7 0 0 0 0 0 0 0 7 0 % I
% Lys: 13 82 0 0 7 0 75 7 0 7 0 7 63 0 13 % K
% Leu: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 57 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 25 0 0 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 13 7 0 0 88 0 % P
% Gln: 0 0 0 0 7 7 0 0 7 0 0 0 0 0 0 % Q
% Arg: 69 0 0 0 0 0 0 0 0 13 69 0 13 0 7 % R
% Ser: 0 0 0 0 50 0 0 7 0 50 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 75 0 82 0 0 0 0 7 0 0 % T
% Val: 0 0 44 0 0 7 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _