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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIB All Species: 46.97
Human Site: Y133 Identified Species: 68.89
UniProt: P23284 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23284 NP_000933.1 216 23743 Y133 E N F K L K H Y G P G W V S M
Chimpanzee Pan troglodytes XP_001174161 216 23752 Y133 E N F K L K H Y G P G W V S M
Rhesus Macaque Macaca mulatta XP_001106524 170 18582 D117 T V K T A W L D G K H V V F G
Dog Lupus familis XP_852389 216 23757 Y133 E N F K L K H Y G P G W V S M
Cat Felis silvestris
Mouse Mus musculus P24369 216 23695 Y133 E N F K L K H Y G P G W V S M
Rat Rattus norvegicus P24368 216 23784 Y133 E N F K L K H Y G P G W V S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508975 216 23586 Y133 E N F K L K H Y G P G W V S M
Chicken Gallus gallus P24367 207 22394 Y124 E N F K L K H Y G P G W V S M
Frog Xenopus laevis NP_001080505 216 23841 Y133 E N F K L K H Y G P F W L S M
Zebra Danio Brachydanio rerio NP_998184 216 23910 Y133 E N F K L K H Y G P G W L S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 T156 E N F E L K H T G S G I L S M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52013 204 21909 A128 G W L S M A N A G A D T N G S
Sea Urchin Strong. purpuratus XP_780268 211 22854 Y126 E N F K L S H Y G A G W L S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASS6 259 28288 V182 E N F K L S H V G P G V L S M
Baker's Yeast Sacchar. cerevisiae P35176 225 25308 D124 E N F D V K H D K P G R L S M
Red Bread Mold Neurospora crassa Q7S7Z6 285 30725 S124 E N F K L K H S K K G L L S M
Conservation
Percent
Protein Identity: 100 99.5 78.2 95.8 N.A. 93.9 93.5 N.A. 89.3 82.8 86.5 81 N.A. 49.3 N.A. 63.4 65.7
Protein Similarity: 100 99.5 78.6 97.6 N.A. 96.7 96.3 N.A. 93.9 88.8 93 89.8 N.A. 65.1 N.A. 75.9 78.7
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 86.6 93.3 N.A. 66.6 N.A. 6.6 80
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 80 N.A. 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. 48.2 50.2 50.1
Protein Similarity: N.A. N.A. N.A. 64.8 65.7 61.4
P-Site Identity: N.A. N.A. N.A. 73.3 60 66.6
P-Site Similarity: N.A. N.A. N.A. 80 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 7 0 7 0 13 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 13 0 0 7 0 0 0 0 % D
% Glu: 88 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 88 0 0 0 0 0 0 0 7 0 0 7 0 % F
% Gly: 7 0 0 0 0 0 0 0 88 0 82 0 0 7 7 % G
% His: 0 0 0 0 0 0 88 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 7 75 0 75 0 0 13 13 0 0 0 0 0 % K
% Leu: 0 0 7 0 82 0 7 0 0 0 0 7 44 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 88 % M
% Asn: 0 88 0 0 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 69 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % R
% Ser: 0 0 0 7 0 13 0 7 0 7 0 0 0 88 7 % S
% Thr: 7 0 0 7 0 0 0 7 0 0 0 7 0 0 0 % T
% Val: 0 7 0 0 7 0 0 7 0 0 0 13 50 0 0 % V
% Trp: 0 7 0 0 0 7 0 0 0 0 0 63 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _