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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: S100A1 All Species: 24.85
Human Site: S43 Identified Species: 60.74
UniProt: P23297 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23297 NP_006262.1 94 10546 S43 E L L Q T E L S G F L D A Q K
Chimpanzee Pan troglodytes XP_513820 147 15819 S96 E L L Q T E L S G F L D A Q K
Rhesus Macaque Macaca mulatta XP_001111052 147 15794 S96 E L L Q T E L S G F L D A Q K
Dog Lupus familis XP_537265 94 10498 S43 E L L Q T E L S G F L D A Q K
Cat Felis silvestris
Mouse Mus musculus P56565 94 10486 S43 D L L Q T E L S G F L D V Q K
Rat Rattus norvegicus P35467 94 10541 S43 D L L Q T E L S S F L D V Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513822 99 11468 H43 Q L L N S E L H D F L S C Q K
Chicken Gallus gallus P27003 97 11272 L43 E K E F P G F L E N Q R D P M
Frog Xenopus laevis P27004 96 11311 L45 D S E F S E F L K N Q N D P M
Zebra Danio Brachydanio rerio NP_001082820 96 10769 S43 S L L Q G E L S D F L A A S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.9 63.9 97.8 N.A. 92.5 93.6 N.A. 59.5 45.3 39.5 69.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.9 63.9 98.9 N.A. 96.8 96.8 N.A. 74.7 69 61.4 77 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 80 N.A. 53.3 6.6 6.6 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 66.6 6.6 26.6 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 30 0 0 0 0 0 0 0 20 0 0 60 20 0 0 % D
% Glu: 50 0 20 0 0 90 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 20 0 0 20 0 0 80 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 0 0 50 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 80 % K
% Leu: 0 80 80 0 0 0 80 20 0 0 80 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 10 0 0 0 0 0 20 0 10 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 20 0 % P
% Gln: 10 0 0 70 0 0 0 0 0 0 20 0 0 70 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 10 10 0 0 20 0 0 70 10 0 0 10 0 10 0 % S
% Thr: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _