KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME2
All Species:
14.24
Human Site:
S360
Identified Species:
26.11
UniProt:
P23368
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23368
NP_002387.1
584
65444
S360
G
R
K
A
K
I
D
S
Y
Q
E
P
F
T
H
Chimpanzee
Pan troglodytes
XP_001154897
584
65469
S360
G
R
K
A
K
I
D
S
Y
Q
E
P
F
T
H
Rhesus Macaque
Macaca mulatta
XP_001099883
959
105776
S360
G
R
K
A
K
I
D
S
Y
Q
E
P
F
T
H
Dog
Lupus familis
XP_849530
584
65328
N360
G
R
K
A
K
I
E
N
H
Q
E
P
F
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99KE1
589
65781
S360
G
R
T
A
S
I
D
S
N
Q
E
P
Y
A
H
Rat
Rattus norvegicus
P13697
572
63984
L347
I
V
K
G
R
A
S
L
T
E
E
K
E
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509137
583
65380
G360
G
R
K
D
G
I
D
G
H
Q
E
A
F
A
H
Chicken
Gallus gallus
NP_989634
557
61982
A334
G
S
I
V
K
G
R
A
S
L
T
E
E
K
S
Frog
Xenopus laevis
NP_001082582
583
65390
G360
G
R
G
E
G
I
D
G
N
Q
E
L
F
A
H
Zebra Danio
Brachydanio rerio
NP_001003627
581
64913
D353
K
Y
G
L
L
V
K
D
R
A
Y
E
T
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
G356
S
R
G
L
I
V
Q
G
R
P
S
G
G
I
T
Poplar Tree
Populus trichocarpa
P34105
591
65205
T365
S
K
T
P
L
E
E
T
R
K
K
I
W
L
T
Maize
Zea mays
P16243
636
69805
A384
Q
T
Y
L
F
L
G
A
G
E
A
G
T
G
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
58.5
91.6
N.A.
88.2
54.2
N.A.
85.4
55.3
76.3
75
N.A.
N.A.
N.A.
N.A.
55.3
Protein Similarity:
100
99.8
60
96
N.A.
93.7
71.9
N.A.
92.2
70.8
86.8
87.3
N.A.
N.A.
N.A.
N.A.
72.6
P-Site Identity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
60
13.3
53.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
26.6
N.A.
66.6
20
53.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
47.5
44
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.6
61.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
39
0
8
0
16
0
8
8
8
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
47
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
8
0
8
16
0
0
16
62
16
16
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
47
0
8
% F
% Gly:
62
0
24
8
16
8
8
24
8
0
0
16
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
54
% H
% Ile:
8
0
8
0
8
54
0
0
0
0
0
8
0
8
8
% I
% Lys:
8
8
47
0
39
0
8
0
0
8
8
8
0
8
0
% K
% Leu:
0
0
0
24
16
8
0
8
0
8
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
8
0
39
0
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
54
0
0
0
0
0
% Q
% Arg:
0
62
0
0
8
0
8
0
24
0
0
0
0
0
0
% R
% Ser:
16
8
0
0
8
0
8
31
8
0
8
0
0
0
16
% S
% Thr:
0
8
16
0
0
0
0
8
8
0
8
0
16
24
16
% T
% Val:
0
8
0
8
0
16
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
24
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _