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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME2
All Species:
30.91
Human Site:
S420
Identified Species:
56.67
UniProt:
P23368
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23368
NP_002387.1
584
65444
S420
R
P
V
I
F
A
L
S
N
P
T
A
Q
A
E
Chimpanzee
Pan troglodytes
XP_001154897
584
65469
S420
R
P
V
I
F
A
L
S
N
P
T
A
Q
A
E
Rhesus Macaque
Macaca mulatta
XP_001099883
959
105776
S420
R
P
V
I
F
A
L
S
N
P
T
A
Q
A
E
Dog
Lupus familis
XP_849530
584
65328
S420
R
P
V
I
F
A
L
S
N
P
T
A
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KE1
589
65781
S420
R
P
I
I
F
A
L
S
N
P
T
A
Q
A
E
Rat
Rattus norvegicus
P13697
572
63984
S407
R
P
I
I
F
A
L
S
N
P
T
S
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509137
583
65380
S420
R
P
V
I
F
A
L
S
N
P
T
V
K
A
E
Chicken
Gallus gallus
NP_989634
557
61982
A394
N
K
N
P
I
I
F
A
L
S
N
P
T
S
K
Frog
Xenopus laevis
NP_001082582
583
65390
S420
R
P
I
I
F
A
L
S
N
P
T
L
K
A
E
Zebra Danio
Brachydanio rerio
NP_001003627
581
64913
P413
M
G
N
L
N
E
R
P
I
I
F
A
L
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
P416
M
A
S
F
N
K
R
P
V
I
F
A
L
S
N
Poplar Tree
Populus trichocarpa
P34105
591
65205
F425
T
S
G
V
G
K
T
F
T
K
E
V
I
E
A
Maize
Zea mays
P16243
636
69805
P444
P
W
A
H
E
H
E
P
L
K
T
L
Y
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
58.5
91.6
N.A.
88.2
54.2
N.A.
85.4
55.3
76.3
75
N.A.
N.A.
N.A.
N.A.
55.3
Protein Similarity:
100
99.8
60
96
N.A.
93.7
71.9
N.A.
92.2
70.8
86.8
87.3
N.A.
N.A.
N.A.
N.A.
72.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
80
N.A.
86.6
0
80
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
20
93.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
47.5
44
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.6
61.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
62
0
8
0
0
0
54
0
62
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
8
8
0
0
0
8
0
0
8
62
% E
% Phe:
0
0
0
8
62
0
8
8
0
0
16
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
62
8
8
0
0
8
16
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
16
0
0
0
16
0
0
24
0
8
% K
% Leu:
0
0
0
8
0
0
62
0
16
0
0
16
16
0
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
16
0
16
0
0
0
62
0
8
0
0
0
16
% N
% Pro:
8
62
0
8
0
0
0
24
0
62
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% Q
% Arg:
62
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
62
0
8
0
8
0
24
0
% S
% Thr:
8
0
0
0
0
0
8
0
8
0
70
0
8
0
0
% T
% Val:
0
0
39
8
0
0
0
0
8
0
0
16
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _