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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLDC All Species: 30.91
Human Site: S564 Identified Species: 85
UniProt: P23378 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23378 NP_000161.2 1020 112730 S564 S C T M K L N S S S E L A P I
Chimpanzee Pan troglodytes XP_001143144 1020 112758 S564 S C T M K L N S S S E L A P I
Rhesus Macaque Macaca mulatta XP_001112651 1020 112774 S564 S C T M K L N S S S E L A P I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W43 1025 113249 S569 S C T M K L N S S S E L A P I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15505 1004 111834 S548 S C T M K L N S S A E L A P I
Frog Xenopus laevis NP_001080141 1024 113513 S569 S C T M K L N S S S E L T P I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649989 985 109695 S540 S C T M K L N S T T E M M P C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177631 1030 113776 S573 S C T M K L N S T S E L A P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80988 1044 113757 A590 S C T M K L N A T T E M M P V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 N.A. N.A. 92 N.A. N.A. N.A. 82.3 82.6 N.A. N.A. 61.5 N.A. N.A. 60
Protein Similarity: 100 99.6 99.6 N.A. N.A. 95.4 N.A. N.A. N.A. 90.6 90.9 N.A. N.A. 75.2 N.A. N.A. 76.2
P-Site Identity: 100 100 100 N.A. N.A. 100 N.A. N.A. N.A. 93.3 93.3 N.A. N.A. 66.6 N.A. N.A. 93.3
P-Site Similarity: 100 100 100 N.A. N.A. 100 N.A. N.A. N.A. 100 93.3 N.A. N.A. 86.6 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 53.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 69.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 60 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 12 0 0 67 0 0 % A
% Cys: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 12 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % I
% Lys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 78 0 0 0 % L
% Met: 0 0 0 100 0 0 0 0 0 0 0 23 23 0 0 % M
% Asn: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 100 0 0 0 0 0 0 89 67 67 0 0 0 0 0 % S
% Thr: 0 0 100 0 0 0 0 0 34 23 0 0 12 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _