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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLRA1 All Species: 11.52
Human Site: S354 Identified Species: 25.33
UniProt: P23415 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23415 NP_000162.2 457 52624 S354 R K R R H H K S P M L N L F Q
Chimpanzee Pan troglodytes XP_001169252 366 42448 G275 H H K E D E A G E G R F N F S
Rhesus Macaque Macaca mulatta XP_001099263 464 53340 A361 R Q K R Q N K A L A L S K F Y
Dog Lupus familis XP_546290 449 51701 R350 L R F R R K R R H H K E D E A
Cat Felis silvestris
Mouse Mus musculus Q64018 457 52638 S354 R K R R H H K S P M L N L F Q
Rat Rattus norvegicus P07727 457 52598 S354 R K R R H H K S P M L N L F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508794 466 53703 L363 K R R H H K E L E K F L H F S
Chicken Gallus gallus P24045 488 56050 I345 Q K K Q S E R I S K A N N E R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio O93430 444 50747 H347 R F Q R R R R H L K E D E A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94900 456 52288 Q355 K K R R D L E Q A S L D A A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O18276 550 62439 S430 K P K K R S S S P I P P L C R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 75.4 98 N.A. 98.9 98.4 N.A. 92 35.2 N.A. 84.9 N.A. 40.9 N.A. 32 N.A.
Protein Similarity: 100 80 84.4 98.2 N.A. 99.5 99.3 N.A. 93.7 56.3 N.A. 92.1 N.A. 58.8 N.A. 49.8 N.A.
P-Site Identity: 100 6.6 33.3 6.6 N.A. 100 100 N.A. 20 13.3 N.A. 13.3 N.A. 26.6 N.A. 20 N.A.
P-Site Similarity: 100 13.3 66.6 20 N.A. 100 100 N.A. 40 46.6 N.A. 33.3 N.A. 46.6 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 10 10 10 0 10 19 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 19 0 0 0 0 0 0 19 10 0 0 % D
% Glu: 0 0 0 10 0 19 19 0 19 0 10 10 10 19 0 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 10 10 0 55 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 10 % G
% His: 10 10 0 10 37 28 0 10 10 10 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 28 46 37 10 0 19 37 0 0 28 10 0 10 0 0 % K
% Leu: 10 0 0 0 0 10 0 10 19 0 46 10 37 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 37 19 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 37 0 10 10 0 0 0 % P
% Gln: 10 10 10 10 10 0 0 10 0 0 0 0 0 0 28 % Q
% Arg: 46 19 46 64 28 10 28 10 0 0 10 0 0 0 19 % R
% Ser: 0 0 0 0 10 10 10 37 10 10 0 10 0 0 28 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _