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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCSH
All Species:
40.3
Human Site:
Y164
Identified Species:
80.61
UniProt:
P23434
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23434
NP_004474.2
173
18911
Y164
E
L
M
S
E
E
A
Y
E
K
Y
I
K
S
I
Chimpanzee
Pan troglodytes
XP_523434
173
18868
Y164
E
L
M
S
E
E
A
Y
E
K
Y
I
K
S
I
Rhesus Macaque
Macaca mulatta
XP_001118486
178
19393
Y169
E
L
I
S
E
E
T
Y
E
K
Y
K
K
S
I
Dog
Lupus familis
XP_536768
173
18535
Y164
E
L
M
S
E
E
A
Y
E
K
Y
I
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK5
170
18571
Y161
E
L
M
S
E
E
A
Y
E
K
Y
V
K
S
I
Rat
Rattus norvegicus
Q5I0P2
170
18467
Y161
E
L
M
S
E
E
A
Y
E
K
Y
V
K
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508528
135
14665
E127
L
M
S
E
E
A
Y
E
K
Y
I
K
S
I
E
Chicken
Gallus gallus
P11183
164
17992
Y155
E
L
M
S
E
D
A
Y
E
K
Y
I
K
S
I
Frog
Xenopus laevis
NP_001087668
170
18705
Y161
D
L
M
S
E
D
A
Y
E
K
Y
I
K
A
L
Zebra Danio
Brachydanio rerio
NP_001002579
174
18889
Y165
E
L
M
D
E
A
A
Y
E
K
F
I
K
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U616
165
17984
Y155
A
L
M
T
E
D
Q
Y
K
A
F
L
S
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQL0
166
17879
Y155
A
L
M
G
P
K
E
Y
T
K
F
C
E
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
82
87.8
N.A.
82
85.5
N.A.
71.6
72.8
67
62.6
N.A.
45.6
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
85.9
90.1
N.A.
88.4
91.9
N.A.
76.3
81.5
81.5
72.4
N.A.
60.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
100
N.A.
93.3
93.3
N.A.
6.6
93.3
73.3
73.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
20
100
100
86.6
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
17
67
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
9
0
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
67
0
0
9
92
50
9
9
75
0
0
0
9
9
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
9
50
0
9
59
% I
% Lys:
0
0
0
0
0
9
0
0
17
84
0
17
75
0
0
% K
% Leu:
9
92
0
0
0
0
0
0
0
0
0
9
0
0
17
% L
% Met:
0
9
84
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
67
0
0
0
0
0
0
0
0
17
75
9
% S
% Thr:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
92
0
9
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _