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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
19.7
Human Site:
Y62
Identified Species:
30.95
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
Y62
D
H
G
G
V
G
P
Y
E
L
G
M
E
H
C
Chimpanzee
Pan troglodytes
XP_523815
451
50966
E45
A
G
S
E
D
E
L
E
E
G
G
Q
L
N
E
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
Y62
D
H
G
G
V
G
P
Y
E
L
G
M
E
H
C
Dog
Lupus familis
XP_537702
525
59107
Y62
D
H
G
G
V
G
P
Y
E
L
G
M
E
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
Y62
D
H
G
G
V
E
P
Y
E
L
G
M
E
H
C
Rat
Rattus norvegicus
P67999
525
59113
Y62
D
H
G
G
V
G
P
Y
E
L
G
M
E
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
P45
R
G
P
E
K
I
R
P
E
C
F
E
L
L
R
Chicken
Gallus gallus
P18652
752
84421
K60
D
K
G
E
G
V
V
K
E
I
N
I
T
H
H
Frog
Xenopus laevis
P10666
629
71268
T47
V
V
K
E
I
P
I
T
H
H
V
K
E
G
A
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Y46
T
H
C
D
E
G
A
Y
K
E
I
P
I
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
L227
P
T
S
N
S
T
P
L
D
L
D
N
E
A
H
Honey Bee
Apis mellifera
XP_395876
456
51514
E48
S
L
S
S
E
G
V
E
T
V
P
I
S
E
Q
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
M75
P
N
N
G
F
R
L
M
N
W
K
T
D
S
S
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
I48
A
D
G
A
Y
E
S
I
E
V
E
E
V
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
A51
V
F
G
P
M
P
E
A
N
S
E
E
A
C
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
6.6
26.6
6.6
20
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
20
100
100
N.A.
93.3
100
N.A.
6.6
40
13.3
26.6
N.A.
26.6
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
0
0
7
7
0
0
0
0
7
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
34
% C
% Asp:
40
7
0
7
7
0
0
0
7
0
7
0
7
0
7
% D
% Glu:
0
0
0
27
14
20
7
14
60
7
14
20
47
7
7
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
14
54
40
7
40
0
0
0
7
40
0
0
7
0
% G
% His:
0
40
0
0
0
0
0
0
7
7
0
0
0
40
20
% H
% Ile:
0
0
0
0
7
7
7
7
0
7
7
14
7
0
0
% I
% Lys:
0
7
7
0
7
0
0
7
7
0
7
7
0
0
0
% K
% Leu:
0
7
0
0
0
0
14
7
0
40
0
0
14
7
7
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
34
0
0
0
% M
% Asn:
0
7
7
7
0
0
0
0
14
0
7
7
0
7
0
% N
% Pro:
14
0
7
7
0
14
40
7
0
0
7
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
7
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
20
7
7
0
7
0
0
7
0
0
7
14
7
% S
% Thr:
7
7
0
0
0
7
0
7
7
0
0
7
7
7
0
% T
% Val:
14
7
0
0
34
7
14
0
0
14
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _