Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRZ1 All Species: 10.61
Human Site: S2056 Identified Species: 25.93
UniProt: P23471 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23471 NP_002842.2 2315 254587 S2056 R E K N R T S S I I P V E R S
Chimpanzee Pan troglodytes XP_001144786 2315 254683 S2056 R E K N R T S S I I P V E R S
Rhesus Macaque Macaca mulatta XP_001083149 2319 261044 E2057 N A T G K R I E L L L S S L W
Dog Lupus familis XP_539545 1926 210053 L1700 T Q Y E K R R L R L H M G D E
Cat Felis silvestris
Mouse Mus musculus Q05909 1442 161224 E1216 M G Y Y R S N E F I I T Q H P
Rat Rattus norvegicus Q62656 2316 255324 S2057 R E K N R T S S I I P V E R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507441 1902 205873 S1676 Y I M G Y Y Q S N E F I I T Q
Chicken Gallus gallus Q98936 1422 159748 E1196 M G Y Y R S N E N V I T Q H P
Frog Xenopus laevis NP_001084180 2271 252519 S2037 G T D Y I N A S Y V M G Y H E
Zebra Danio Brachydanio rerio A4IFW2 1909 213435 V1683 M P F E S T R V C L Q P I R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 55.7 53.6 N.A. 32.4 82.1 N.A. 53 32.7 52.2 23.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 64.9 62.3 N.A. 44.7 89.3 N.A. 62.5 45.6 66.6 39.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 13.3 100 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 26.6 N.A. 33.3 100 N.A. 13.3 33.3 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 30 0 20 0 0 0 30 0 10 0 0 30 0 20 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 10 0 0 0 0 % F
% Gly: 10 20 0 20 0 0 0 0 0 0 0 10 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 30 0 % H
% Ile: 0 10 0 0 10 0 10 0 30 40 20 10 20 0 0 % I
% Lys: 0 0 30 0 20 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 10 30 10 0 0 10 0 % L
% Met: 30 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 10 0 0 30 0 10 20 0 20 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 30 10 0 0 20 % P
% Gln: 0 10 0 0 0 0 10 0 0 0 10 0 20 0 10 % Q
% Arg: 30 0 0 0 50 20 20 0 10 0 0 0 0 40 0 % R
% Ser: 0 0 0 0 10 20 30 50 0 0 0 10 10 0 30 % S
% Thr: 10 10 10 0 0 40 0 0 0 0 0 20 0 10 0 % T
% Val: 0 0 0 0 0 0 0 10 0 20 0 30 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 10 0 30 30 10 10 0 0 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _