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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCC All Species: 22.42
Human Site: S184 Identified Species: 44.85
UniProt: P23508 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23508 NP_001078846.1 829 93055 S184 K K S S C S L S V A E V D R H
Chimpanzee Pan troglodytes XP_517879 1064 118580 S369 K K S S C S L S V A E V D R H
Rhesus Macaque Macaca mulatta XP_001082972 1014 112870 S369 K K S S C S L S V A E V D R H
Dog Lupus familis XP_853939 829 92784 S184 K K S S C S L S V A E V D R R
Cat Felis silvestris
Mouse Mus musculus Q8R370 680 74812 K61 Q S P R N W I K E G C D V G S
Rat Rattus norvegicus Q3T1I3 680 74593 K61 Q G P G N R I K E D C D V G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507243 1025 115224 S381 K K S S C S L S V A E V D R H
Chicken Gallus gallus XP_413971 825 92902 S182 K K S S C S L S V A E V D R H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921192 502 56563
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650457 715 80940 N95 C S T L D I V N K V E Q L S V
Honey Bee Apis mellifera XP_392073 831 92638 Q182 L Q A A R A E Q K V E Q Q A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786141 903 100683 E212 E S A E H E V E K L T E A S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 81 97 N.A. 24.8 24.6 N.A. 75.3 95.4 N.A. 20.9 N.A. 22.3 32.4 N.A. 48.7
Protein Similarity: 100 77.9 81.5 98.3 N.A. 42.7 42.9 N.A. 78.2 97.4 N.A. 36 N.A. 43.6 54.1 N.A. 63.9
P-Site Identity: 100 100 100 93.3 N.A. 0 0 N.A. 100 100 N.A. 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 13.3 N.A. 100 100 N.A. 0 N.A. 26.6 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 0 9 0 0 0 50 0 0 9 9 9 % A
% Cys: 9 0 0 0 50 0 0 0 0 0 17 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 9 0 17 50 0 0 % D
% Glu: 9 0 0 9 0 9 9 9 17 0 67 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 0 0 9 0 0 0 17 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 42 % H
% Ile: 0 0 0 0 0 9 17 0 0 0 0 0 0 0 0 % I
% Lys: 50 50 0 0 0 0 0 17 25 0 0 0 0 0 0 % K
% Leu: 9 0 0 9 0 0 50 0 0 9 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 17 9 0 0 0 0 0 9 0 0 0 17 9 0 0 % Q
% Arg: 0 0 0 9 9 9 0 0 0 0 0 0 0 50 9 % R
% Ser: 0 25 50 50 0 50 0 50 0 0 0 0 0 17 17 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 17 0 50 17 0 50 17 0 9 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _