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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCC All Species: 24.55
Human Site: S341 Identified Species: 49.09
UniProt: P23508 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23508 NP_001078846.1 829 93055 S341 K T R S E S S S S D R P V L G
Chimpanzee Pan troglodytes XP_517879 1064 118580 S526 K T R S E S S S S D R P V L G
Rhesus Macaque Macaca mulatta XP_001082972 1014 112870 S526 K T R S E S S S S D R P I L G
Dog Lupus familis XP_853939 829 92784 S341 K T R S E S S S S D R P V L G
Cat Felis silvestris
Mouse Mus musculus Q8R370 680 74812 M213 Q E L E D S L M Q M E A S P P
Rat Rattus norvegicus Q3T1I3 680 74593 M213 Q E L E D S L M Q L E A S P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507243 1025 115224 S538 K T R S E S S S S D R P V L G
Chicken Gallus gallus XP_413971 825 92902 S339 K T R S E S S S S D R P V L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921192 502 56563 L35 L Y K H N Q D L N A S L K S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650457 715 80940 A247 E E V L H L R A R I A L L Q S
Honey Bee Apis mellifera XP_392073 831 92638 D343 N N Q R Q Q A D S E S P R R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786141 903 100683 S411 S S S S R S S S D R C V L G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 81 97 N.A. 24.8 24.6 N.A. 75.3 95.4 N.A. 20.9 N.A. 22.3 32.4 N.A. 48.7
Protein Similarity: 100 77.9 81.5 98.3 N.A. 42.7 42.9 N.A. 78.2 97.4 N.A. 36 N.A. 43.6 54.1 N.A. 63.9
P-Site Identity: 100 100 93.3 100 N.A. 6.6 6.6 N.A. 100 100 N.A. 0 N.A. 0 13.3 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. 100 100 N.A. 13.3 N.A. 20 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 0 9 9 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 9 9 9 50 0 0 0 0 0 % D
% Glu: 9 25 0 17 50 0 0 0 0 9 17 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 50 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % I
% Lys: 50 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 9 0 17 9 0 9 17 9 0 9 0 17 17 50 0 % L
% Met: 0 0 0 0 0 0 0 17 0 9 0 0 0 0 0 % M
% Asn: 9 9 0 0 9 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 59 0 17 17 % P
% Gln: 17 0 9 0 9 17 0 0 17 0 0 0 0 9 0 % Q
% Arg: 0 0 50 9 9 0 9 0 9 9 50 0 9 9 9 % R
% Ser: 9 9 9 59 0 75 59 59 59 0 17 0 17 9 17 % S
% Thr: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 9 42 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _