Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCC All Species: 27.58
Human Site: S405 Identified Species: 55.15
UniProt: P23508 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23508 NP_001078846.1 829 93055 S405 V E T E R L N S R I E H L K S
Chimpanzee Pan troglodytes XP_517879 1064 118580 S590 V E T E R L N S R I E H L K S
Rhesus Macaque Macaca mulatta XP_001082972 1014 112870 S590 V E T E R L N S R I E H L K S
Dog Lupus familis XP_853939 829 92784 S405 V E T E R L N S R I E H L K S
Cat Felis silvestris
Mouse Mus musculus Q8R370 680 74812 P277 L S T Q H P A P E T Y L M E D
Rat Rattus norvegicus Q3T1I3 680 74593 P277 L S T Q R P S P E M Y L M E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507243 1025 115224 S602 V E T E R L N S R I E H L K S
Chicken Gallus gallus XP_413971 825 92902 S403 V E T E R L N S R I E H L K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921192 502 56563 S99 R T S S P C F S S P S Y P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650457 715 80940 V311 V P K M A E R V K L R C A S K
Honey Bee Apis mellifera XP_392073 831 92638 I407 R R T D E R H I T G P D I T N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786141 903 100683 S475 V D L E R L T S K I E H L R C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 81 97 N.A. 24.8 24.6 N.A. 75.3 95.4 N.A. 20.9 N.A. 22.3 32.4 N.A. 48.7
Protein Similarity: 100 77.9 81.5 98.3 N.A. 42.7 42.9 N.A. 78.2 97.4 N.A. 36 N.A. 43.6 54.1 N.A. 63.9
P-Site Identity: 100 100 100 100 N.A. 6.6 13.3 N.A. 100 100 N.A. 13.3 N.A. 6.6 6.6 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 33.3 53.3 N.A. 100 100 N.A. 26.6 N.A. 20 33.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 9 % C
% Asp: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 17 % D
% Glu: 0 50 0 59 9 9 0 0 17 0 59 0 0 17 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % G
% His: 0 0 0 0 9 0 9 0 0 0 0 59 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 59 0 0 9 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 17 0 0 0 0 50 9 % K
% Leu: 17 0 9 0 0 59 0 0 0 9 0 17 59 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 9 0 0 17 0 0 % M
% Asn: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 0 0 9 17 0 17 0 9 9 0 9 0 0 % P
% Gln: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 17 9 0 0 67 9 9 0 50 0 9 0 0 9 0 % R
% Ser: 0 17 9 9 0 0 9 67 9 0 9 0 0 9 59 % S
% Thr: 0 9 75 0 0 0 9 0 9 9 0 0 0 9 0 % T
% Val: 67 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 17 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _