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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCC
All Species:
12.73
Human Site:
S689
Identified Species:
25.45
UniProt:
P23508
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23508
NP_001078846.1
829
93055
S689
L
S
S
T
S
S
G
S
K
D
K
P
G
K
E
Chimpanzee
Pan troglodytes
XP_517879
1064
118580
S874
L
S
S
T
S
S
G
S
K
D
K
P
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001082972
1014
112870
G874
L
S
S
T
S
S
G
G
K
D
K
P
S
K
E
Dog
Lupus familis
XP_853939
829
92784
G689
L
S
S
T
S
S
G
G
K
D
K
P
G
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R370
680
74812
R547
D
E
E
A
G
E
D
R
Q
Q
H
Y
Q
G
P
Rat
Rattus norvegicus
Q3T1I3
680
74593
R547
E
E
E
A
G
E
D
R
Q
Q
H
Y
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507243
1025
115224
S886
L
S
S
A
S
S
G
S
K
D
K
S
G
K
E
Chicken
Gallus gallus
XP_413971
825
92902
S686
L
S
S
T
S
S
G
S
K
D
K
L
G
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921192
502
56563
R369
L
R
D
E
L
G
E
R
R
A
A
Q
Q
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650457
715
80940
E581
L
Q
L
K
T
K
M
E
E
A
E
Q
E
R
Q
Honey Bee
Apis mellifera
XP_392073
831
92638
I678
I
A
A
Q
H
A
A
I
E
H
L
Q
G
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786141
903
100683
P761
T
S
S
S
G
G
G
P
G
G
C
G
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.6
81
97
N.A.
24.8
24.6
N.A.
75.3
95.4
N.A.
20.9
N.A.
22.3
32.4
N.A.
48.7
Protein Similarity:
100
77.9
81.5
98.3
N.A.
42.7
42.9
N.A.
78.2
97.4
N.A.
36
N.A.
43.6
54.1
N.A.
63.9
P-Site Identity:
100
100
86.6
93.3
N.A.
0
0
N.A.
86.6
93.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
6.6
6.6
N.A.
86.6
93.3
N.A.
20
N.A.
40
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
25
0
9
9
0
0
17
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
17
0
0
50
0
0
0
0
0
% D
% Glu:
9
17
17
9
0
17
9
9
17
0
9
0
9
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
25
17
59
17
9
9
0
9
59
25
9
% G
% His:
0
0
0
0
9
0
0
0
0
9
17
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
50
0
50
0
0
50
0
% K
% Leu:
67
0
9
0
9
0
0
0
0
0
9
9
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
34
0
0
17
% P
% Gln:
0
9
0
9
0
0
0
0
17
17
0
25
25
9
9
% Q
% Arg:
0
9
0
0
0
0
0
25
9
0
0
0
0
17
0
% R
% Ser:
0
59
59
9
50
50
0
34
0
0
0
9
9
0
0
% S
% Thr:
9
0
0
42
9
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _