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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCC All Species: 26.67
Human Site: T443 Identified Species: 53.33
UniProt: P23508 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23508 NP_001078846.1 829 93055 T443 G K Y E S N A T A L R L A L Q
Chimpanzee Pan troglodytes XP_517879 1064 118580 T628 G K Y E S N A T A L R L A L Q
Rhesus Macaque Macaca mulatta XP_001082972 1014 112870 T628 G K Y E S N A T A L R L A L Q
Dog Lupus familis XP_853939 829 92784 T443 G K Y E S N A T A L R L A L Q
Cat Felis silvestris
Mouse Mus musculus Q8R370 680 74812 E315 Q G Y K G R C E S L S I K L A
Rat Rattus norvegicus Q3T1I3 680 74593 E315 Q G Y K G R C E S L S I K L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507243 1025 115224 T640 G K Y E S N A T A L R L A L Q
Chicken Gallus gallus XP_413971 825 92902 T441 G K Y E S N A T A L R L A L Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921192 502 56563 K137 V L Q A E T E K M Q R C L E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650457 715 80940 Q349 L V S E L K E Q N L Y M E N F
Honey Bee Apis mellifera XP_392073 831 92638 Q445 E L N G S E K Q F E V E T E R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786141 903 100683 T513 G K Y E S N N T A L Q L A V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 81 97 N.A. 24.8 24.6 N.A. 75.3 95.4 N.A. 20.9 N.A. 22.3 32.4 N.A. 48.7
Protein Similarity: 100 77.9 81.5 98.3 N.A. 42.7 42.9 N.A. 78.2 97.4 N.A. 36 N.A. 43.6 54.1 N.A. 63.9
P-Site Identity: 100 100 100 100 N.A. 20 20 N.A. 100 100 N.A. 6.6 N.A. 13.3 6.6 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 40 40 N.A. 100 100 N.A. 13.3 N.A. 20 13.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 50 0 59 0 0 0 59 0 9 % A
% Cys: 0 0 0 0 0 0 17 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 67 9 9 17 17 0 9 0 9 9 17 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % F
% Gly: 59 17 0 9 17 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % I
% Lys: 0 59 0 17 0 9 9 9 0 0 0 0 17 0 0 % K
% Leu: 9 17 0 0 9 0 0 0 0 84 0 59 9 67 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 59 9 0 9 0 0 0 0 9 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 17 0 9 0 0 0 0 17 0 9 9 0 0 0 50 % Q
% Arg: 0 0 0 0 0 17 0 0 0 0 59 0 0 0 17 % R
% Ser: 0 0 9 0 67 0 0 0 17 0 17 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 59 0 0 0 0 9 0 0 % T
% Val: 9 9 0 0 0 0 0 0 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 75 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _