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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AHCY
All Species:
49.39
Human Site:
S154
Identified Species:
90.56
UniProt:
P23526
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23526
NP_000678.1
432
47716
S154
L
P
G
I
R
G
I
S
E
E
T
T
T
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089745
432
47680
S154
L
S
G
I
R
G
I
S
E
E
T
T
T
G
V
Dog
Lupus familis
XP_851307
434
47897
S156
L
S
G
I
R
G
I
S
E
E
T
T
T
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P50247
432
47670
S154
L
S
G
I
R
G
I
S
E
E
T
T
T
G
V
Rat
Rattus norvegicus
P10760
432
47520
S154
L
S
G
I
R
G
I
S
E
E
T
T
T
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417331
433
47717
S155
L
K
G
I
R
G
I
S
E
E
T
T
T
G
V
Frog
Xenopus laevis
P51893
433
47728
S155
L
K
G
I
K
G
I
S
E
E
T
T
T
G
V
Zebra Danio
Brachydanio rerio
NP_954688
433
47946
S155
L
A
G
I
K
G
I
S
E
E
T
T
T
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27580
432
47348
S154
L
K
N
I
K
G
L
S
E
E
T
T
T
G
V
Honey Bee
Apis mellifera
XP_391917
433
47959
S155
L
K
E
C
R
G
V
S
E
E
T
T
T
G
V
Nematode Worm
Caenorhab. elegans
P27604
437
47517
S156
L
A
G
I
R
G
L
S
E
E
T
T
T
G
V
Sea Urchin
Strong. purpuratus
XP_780172
431
47503
S154
L
P
G
I
K
G
L
S
E
E
T
T
T
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39954
449
49107
S157
L
E
D
C
F
G
L
S
E
E
T
T
T
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
92.1
N.A.
96.9
96.5
N.A.
N.A.
90.3
87.9
86.1
N.A.
81
78.2
76.4
77.3
Protein Similarity:
100
N.A.
97.6
94.6
N.A.
98.6
98.3
N.A.
N.A.
95.3
94.2
93.5
N.A.
87.2
86.8
85.8
87.5
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
86.6
N.A.
73.3
73.3
86.6
86.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
86.6
80
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
70.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
82.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
100
100
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
0
100
0
0
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
85
0
0
62
0
0
0
0
0
0
0
0
% I
% Lys:
0
31
0
0
31
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
100
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
31
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
100
100
100
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _