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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AHCY
All Species:
37.27
Human Site:
Y39
Identified Species:
68.33
UniProt:
P23526
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23526
NP_000678.1
432
47716
Y39
L
M
R
M
R
E
R
Y
S
A
S
K
P
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089745
432
47680
Y39
L
M
R
M
R
E
Q
Y
L
A
S
K
P
L
K
Dog
Lupus familis
XP_851307
434
47897
Y39
L
M
R
M
R
E
M
Y
S
A
S
K
P
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P50247
432
47670
Y39
L
M
R
M
R
E
M
Y
S
A
S
K
P
L
K
Rat
Rattus norvegicus
P10760
432
47520
Y39
L
M
R
M
R
E
M
Y
S
A
S
K
P
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417331
433
47717
Y39
L
M
K
M
R
E
M
Y
G
A
S
K
P
L
K
Frog
Xenopus laevis
P51893
433
47728
H39
L
M
K
M
R
E
M
H
S
E
S
K
P
L
K
Zebra Danio
Brachydanio rerio
NP_954688
433
47946
Y39
L
M
K
M
R
E
L
Y
G
Q
S
K
P
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27580
432
47348
Y38
L
M
A
C
R
K
K
Y
G
P
S
K
P
L
K
Honey Bee
Apis mellifera
XP_391917
433
47959
Y39
L
M
A
I
R
K
K
Y
G
P
Q
K
I
L
K
Nematode Worm
Caenorhab. elegans
P27604
437
47517
Y40
L
M
A
M
R
S
K
Y
G
P
S
Q
P
L
K
Sea Urchin
Strong. purpuratus
XP_780172
431
47503
H38
L
M
Q
M
R
K
K
H
G
P
S
K
P
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39954
449
49107
Y40
L
M
A
I
R
K
A
Y
G
D
V
Q
P
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
92.1
N.A.
96.9
96.5
N.A.
N.A.
90.3
87.9
86.1
N.A.
81
78.2
76.4
77.3
Protein Similarity:
100
N.A.
97.6
94.6
N.A.
98.6
98.3
N.A.
N.A.
95.3
94.2
93.5
N.A.
87.2
86.8
85.8
87.5
P-Site Identity:
100
N.A.
86.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
73.3
73.3
N.A.
60
46.6
60
60
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
80
N.A.
73.3
66.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
70.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
82.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
0
8
0
0
47
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
62
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
24
0
0
31
31
0
0
0
0
85
0
0
100
% K
% Leu:
100
0
0
0
0
0
8
0
8
0
0
0
0
100
0
% L
% Met:
0
100
0
77
0
0
39
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
31
0
0
93
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
8
8
16
0
0
0
% Q
% Arg:
0
0
39
0
100
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
39
0
85
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _