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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BDNF
All Species:
22.42
Human Site:
S139
Identified Species:
54.81
UniProt:
P23560
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23560
NP_001137277.1
247
27818
S139
P
A
R
R
G
E
L
S
V
C
D
S
I
S
E
Chimpanzee
Pan troglodytes
XP_522331
257
29493
E148
E
H
K
S
H
R
G
E
Y
S
V
C
D
S
E
Rhesus Macaque
Macaca mulatta
Q06225
114
12937
Dog
Lupus familis
XP_543858
257
29366
E148
E
H
K
S
H
R
G
E
Y
S
V
C
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P21237
249
28105
S141
P
A
R
R
G
E
L
S
V
C
D
S
I
S
E
Rat
Rattus norvegicus
P23363
249
28091
S141
P
A
R
R
G
E
L
S
V
C
D
S
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511980
272
30461
S164
P
A
R
R
G
E
L
S
V
C
D
S
I
S
E
Chicken
Gallus gallus
P25429
246
27696
S138
P
A
R
R
G
E
L
S
V
C
D
S
T
S
E
Frog
Xenopus laevis
P25432
114
13012
Zebra Danio
Brachydanio rerio
NP_571670
270
29434
S162
P
A
R
R
G
E
L
S
V
C
D
S
I
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.9
46.1
39.6
N.A.
96.7
96.7
N.A.
82.7
91.5
42.9
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.2
46.1
55.6
N.A.
97.9
97.9
N.A.
88.2
95.5
44.9
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
13.3
N.A.
100
100
N.A.
100
93.3
0
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
0
20
N.A.
100
100
N.A.
100
93.3
0
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
60
0
20
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
60
0
20
0
0
% D
% Glu:
20
0
0
0
0
60
0
20
0
0
0
0
0
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
60
0
20
0
0
0
0
0
0
0
0
% G
% His:
0
20
0
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
60
60
0
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
20
0
0
0
60
0
20
0
60
0
80
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
60
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _