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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP2B4 All Species: 20.61
Human Site: S841 Identified Species: 50.37
UniProt: P23634 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23634 NP_001001396.1 1241 137920 S841 R N V Y D S I S K F L Q F Q L
Chimpanzee Pan troglodytes XP_001156068 1241 137888 S841 R N V Y D S I S K F L Q F Q L
Rhesus Macaque Macaca mulatta NP_001028098 1205 133638 Y837 V M W G R N V Y D S I S K F L
Dog Lupus familis XP_848332 1242 137803 S841 R N V Y D S I S K F L Q F Q L
Cat Felis silvestris
Mouse Mus musculus Q9R0K7 1198 132569 S831 R N V Y D S I S K F L Q F Q L
Rat Rattus norvegicus Q64542 1203 133076 Y837 V M W G R N V Y D S I S K F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518636 1216 134041 S841 R N V Y D S I S K F L Q F Q L
Chicken Gallus gallus Q9YGL9 1042 115411 R678 R E A R C F A R V E P A H K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2L4 1025 111926 C661 V R E A V Q T C Q A A G I T V
Baker's Yeast Sacchar. cerevisiae P38929 1173 130843 M791 S S E A Y S A M E G T E F R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 95.3 90.8 N.A. 70.9 82.1 N.A. 78.8 21.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 96.4 95 N.A. 81.1 88.7 N.A. 86.5 39.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 6.6 N.A. 100 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 26.6 N.A. 100 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.7 21.3 N.A.
Protein Similarity: N.A. N.A. N.A. 48 39.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 20 0 0 20 0 0 10 10 10 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 0 20 0 0 0 0 0 0 % D
% Glu: 0 10 20 0 0 0 0 0 10 10 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 50 0 0 60 20 0 % F
% Gly: 0 0 0 20 0 0 0 0 0 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 50 0 0 0 20 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 50 0 0 0 20 10 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 70 % L
% Met: 0 20 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 50 0 0 0 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 10 0 0 50 0 50 0 % Q
% Arg: 60 10 0 10 20 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 10 10 0 0 0 60 0 50 0 20 0 20 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 10 0 0 10 0 % T
% Val: 30 0 50 0 10 0 20 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 50 10 0 0 20 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _