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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
27.27
Human Site:
Y258
Identified Species:
54.55
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
Y258
L
P
C
E
V
S
T
Y
A
K
S
R
K
D
I
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
V189
S
L
T
G
L
H
C
V
W
C
H
L
E
I
H
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
Y258
L
P
C
E
V
S
T
Y
A
K
S
R
K
D
I
Dog
Lupus familis
XP_531626
735
82556
Y258
L
P
C
E
V
S
T
Y
A
K
S
R
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
Y259
Q
P
C
E
V
S
T
Y
A
K
S
R
K
D
I
Rat
Rattus norvegicus
P51556
727
82180
Y256
Q
P
C
E
V
S
T
Y
A
K
S
R
K
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
T296
A
P
A
S
C
I
K
T
Y
V
K
S
K
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
Y261
P
A
P
C
T
R
T
Y
V
M
S
K
K
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
Y436
P
A
S
C
I
T
T
Y
V
K
S
K
K
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
Y320
A
T
N
C
I
R
T
Y
S
S
R
Q
Q
D
K
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
T726
A
P
A
C
C
I
S
T
Y
V
K
S
K
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
Y264
I
R
I
Q
S
K
K
Y
K
Q
T
N
E
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
33.3
N.A.
20
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
40
N.A.
53.3
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
17
17
0
0
0
0
0
42
0
0
0
0
0
0
% A
% Cys:
0
0
42
34
17
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% D
% Glu:
0
0
0
42
0
0
0
0
0
0
0
0
17
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% H
% Ile:
9
0
9
0
17
17
0
0
0
0
0
0
0
9
42
% I
% Lys:
0
0
0
0
0
9
17
0
9
50
17
17
75
9
17
% K
% Leu:
25
9
0
0
9
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
17
59
9
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
17
0
0
9
0
0
0
0
0
9
0
9
9
0
0
% Q
% Arg:
0
9
0
0
0
17
0
0
0
0
9
42
0
9
0
% R
% Ser:
9
0
9
9
9
42
9
0
9
9
59
17
0
0
9
% S
% Thr:
0
9
9
0
9
9
67
17
0
0
9
0
0
9
17
% T
% Val:
0
0
0
0
42
0
0
9
17
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _