KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
4.55
Human Site:
Y623
Identified Species:
9.09
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
Y623
R
R
P
H
G
D
I
Y
G
I
N
Q
A
L
G
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
A516
D
I
Y
G
I
N
Q
A
L
G
A
T
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
Y623
R
K
P
H
G
D
I
Y
G
I
N
Q
A
L
G
Dog
Lupus familis
XP_531626
735
82556
H623
K
K
P
H
G
D
I
H
G
I
N
Q
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
C618
K
R
P
H
G
D
T
C
E
I
N
Q
A
L
G
Rat
Rattus norvegicus
P51556
727
82180
C615
K
R
P
H
G
D
T
C
G
I
N
Q
A
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
R683
K
K
R
R
S
H
R
R
T
E
K
K
R
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
K620
S
N
L
W
G
E
A
K
K
S
D
R
M
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
R1087
H
L
S
Q
K
R
I
R
K
S
A
G
P
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
M681
S
R
K
S
K
G
R
M
P
G
L
F
P
M
K
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
L1105
S
I
Y
G
G
S
N
L
W
G
D
T
P
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
P610
E
T
Y
E
N
F
D
P
Q
S
M
H
D
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
6.6
93.3
80
N.A.
73.3
80
N.A.
N.A.
0
N.A.
6.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
80
86.6
N.A.
N.A.
20
N.A.
26.6
N.A.
13.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
0
17
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
42
9
0
0
0
17
0
9
9
9
% D
% Glu:
9
0
0
9
0
9
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
17
59
9
0
0
34
25
0
9
0
0
50
% G
% His:
9
0
0
42
0
9
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
17
0
0
9
0
34
0
0
42
0
0
0
0
9
% I
% Lys:
34
25
9
0
17
0
0
9
17
0
9
9
0
17
17
% K
% Leu:
0
9
9
0
0
0
0
9
9
0
9
0
0
42
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
9
0
9
9
0
% M
% Asn:
0
9
0
0
9
9
9
0
0
0
42
0
0
0
0
% N
% Pro:
0
0
42
0
0
0
0
9
9
0
0
0
25
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
9
0
0
42
0
0
9
% Q
% Arg:
17
34
9
9
0
9
17
17
0
0
0
9
9
0
0
% R
% Ser:
25
0
9
9
9
9
0
0
0
25
0
0
0
17
0
% S
% Thr:
0
9
0
0
0
0
17
0
9
0
0
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
25
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _