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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTYMK
All Species:
24.24
Human Site:
S183
Identified Species:
38.1
UniProt:
P23919
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23919
NP_036277.2
212
23819
S183
K
M
V
D
A
S
K
S
I
E
A
V
H
E
D
Chimpanzee
Pan troglodytes
XP_001161682
169
19013
S140
K
M
V
D
A
S
K
S
I
E
A
V
H
E
D
Rhesus Macaque
Macaca mulatta
XP_001094132
212
23926
S183
K
M
V
D
A
S
K
S
I
E
A
V
H
E
D
Dog
Lupus familis
XP_851996
156
17492
E129
V
D
A
S
K
S
I
E
A
V
H
K
E
I
H
Cat
Felis silvestris
Mouse
Mus musculus
P97930
212
23896
S183
K
V
V
D
A
S
K
S
I
E
E
V
H
K
E
Rat
Rattus norvegicus
NP_001100395
212
23955
S183
K
V
V
D
A
S
K
S
I
E
D
V
H
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513078
670
74072
N640
K
V
I
D
A
S
K
N
I
E
D
L
H
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032187
212
24114
T183
K
V
I
D
A
A
R
T
I
E
E
V
H
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611290
211
23800
S183
H
Q
F
D
A
R
Q
S
V
E
D
L
H
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22018
218
24324
D191
K
T
V
N
A
D
G
D
L
D
S
V
E
K
N
Sea Urchin
Strong. purpuratus
XP_784160
171
19446
K140
V
S
S
E
A
A
E
K
R
G
G
F
G
E
E
Poplar Tree
Populus trichocarpa
XP_002298600
222
24888
P191
K
V
I
D
A
C
Q
P
I
E
D
I
E
K
Q
Maize
Zea mays
NP_001150303
255
27917
P226
K
V
V
D
G
F
L
P
M
E
T
V
E
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001078772
271
30359
A240
K
I
I
N
A
S
D
A
M
E
E
V
E
K
K
Baker's Yeast
Sacchar. cerevisiae
P00572
216
24669
G188
I
V
D
V
T
N
K
G
I
Q
E
V
E
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.7
95.7
55.1
N.A.
81.1
81.1
N.A.
24.1
N.A.
N.A.
64.1
N.A.
44.8
N.A.
40.3
51.8
Protein Similarity:
100
79.7
98.5
64.1
N.A.
90.5
89.6
N.A.
29.1
N.A.
N.A.
83.9
N.A.
61.7
N.A.
64.2
65.5
P-Site Identity:
100
100
100
6.6
N.A.
73.3
80
N.A.
53.3
N.A.
N.A.
53.3
N.A.
33.3
N.A.
26.6
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
93.3
N.A.
53.3
N.A.
66.6
40
Percent
Protein Identity:
44.5
38
N.A.
38
43.9
N.A.
Protein Similarity:
67.5
53.3
N.A.
55.7
61.1
N.A.
P-Site Identity:
33.3
40
N.A.
33.3
20
N.A.
P-Site Similarity:
66.6
53.3
N.A.
73.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
80
14
0
7
7
0
20
0
0
14
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
67
0
7
7
7
0
7
27
0
0
0
27
% D
% Glu:
0
0
0
7
0
0
7
7
0
74
27
0
40
40
27
% E
% Phe:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
7
0
7
7
0
7
7
0
7
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
7
0
54
0
7
% H
% Ile:
7
7
27
0
0
0
7
0
60
0
0
7
0
7
0
% I
% Lys:
74
0
0
0
7
0
47
7
0
0
0
7
0
40
7
% K
% Leu:
0
0
0
0
0
0
7
0
7
0
0
14
0
0
7
% L
% Met:
0
20
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
7
0
7
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
14
0
0
7
0
0
0
0
14
% Q
% Arg:
0
0
0
0
0
7
7
0
7
0
0
0
0
0
7
% R
% Ser:
0
7
7
7
0
54
0
40
0
0
7
0
0
0
0
% S
% Thr:
0
7
0
0
7
0
0
7
0
0
7
0
0
0
0
% T
% Val:
14
47
47
7
0
0
0
0
7
7
0
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _