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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTYMK
All Species:
29.39
Human Site:
S195
Identified Species:
46.19
UniProt:
P23919
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23919
NP_036277.2
212
23819
S195
H
E
D
I
R
V
L
S
E
D
A
I
R
T
A
Chimpanzee
Pan troglodytes
XP_001161682
169
19013
S152
H
E
D
I
R
V
L
S
E
D
A
I
R
T
A
Rhesus Macaque
Macaca mulatta
XP_001094132
212
23926
S195
H
E
D
I
R
V
L
S
E
D
A
I
H
T
A
Dog
Lupus familis
XP_851996
156
17492
D141
E
I
H
A
L
S
V
D
T
M
Q
A
A
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97930
212
23896
S195
H
K
E
I
R
A
H
S
E
D
A
I
R
N
A
Rat
Rattus norvegicus
NP_001100395
212
23955
S195
H
E
E
I
R
A
L
S
E
D
A
I
Q
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513078
670
74072
S652
H
K
E
I
H
H
L
S
K
E
A
I
K
E
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032187
212
24114
S195
H
K
D
I
K
D
L
S
E
N
I
I
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611290
211
23800
T195
H
A
Q
I
A
S
I
T
E
E
L
L
P
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22018
218
24324
Y203
E
K
N
V
F
R
I
Y
E
N
L
D
R
E
K
Sea Urchin
Strong. purpuratus
XP_784160
171
19446
S152
G
E
E
R
Y
E
K
S
E
I
Q
A
R
V
A
Poplar Tree
Populus trichocarpa
XP_002298600
222
24888
V203
E
K
Q
L
Q
D
A
V
L
D
H
V
M
A
C
Maize
Zea mays
NP_001150303
255
27917
A238
E
E
R
L
R
D
L
A
T
S
C
I
Q
D
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001078772
271
30359
V252
E
K
K
I
Q
Q
V
V
L
D
Q
V
K
E
C
Baker's Yeast
Sacchar. cerevisiae
P00572
216
24669
V200
E
A
L
I
W
Q
I
V
E
P
V
L
S
T
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.7
95.7
55.1
N.A.
81.1
81.1
N.A.
24.1
N.A.
N.A.
64.1
N.A.
44.8
N.A.
40.3
51.8
Protein Similarity:
100
79.7
98.5
64.1
N.A.
90.5
89.6
N.A.
29.1
N.A.
N.A.
83.9
N.A.
61.7
N.A.
64.2
65.5
P-Site Identity:
100
100
93.3
0
N.A.
66.6
73.3
N.A.
46.6
N.A.
N.A.
53.3
N.A.
20
N.A.
13.3
33.3
P-Site Similarity:
100
100
93.3
6.6
N.A.
80
86.6
N.A.
80
N.A.
N.A.
73.3
N.A.
46.6
N.A.
46.6
40
Percent
Protein Identity:
44.5
38
N.A.
38
43.9
N.A.
Protein Similarity:
67.5
53.3
N.A.
55.7
61.1
N.A.
P-Site Identity:
6.6
26.6
N.A.
13.3
20
N.A.
P-Site Similarity:
33.3
46.6
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
7
14
7
7
0
0
40
14
7
14
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
20
% C
% Asp:
0
0
27
0
0
20
0
7
0
47
0
7
0
7
0
% D
% Glu:
40
40
27
0
0
7
0
0
67
14
0
0
0
20
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
54
0
7
0
7
7
7
0
0
0
7
0
7
0
7
% H
% Ile:
0
7
0
67
0
0
20
0
0
7
7
54
0
0
0
% I
% Lys:
0
40
7
0
7
0
7
0
7
0
0
0
14
7
7
% K
% Leu:
0
0
7
14
7
0
47
0
14
0
14
14
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
14
0
0
0
14
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% P
% Gln:
0
0
14
0
14
14
0
0
0
0
20
0
14
0
7
% Q
% Arg:
0
0
7
7
40
7
0
0
0
0
0
0
34
0
0
% R
% Ser:
0
0
0
0
0
14
0
54
0
7
0
0
14
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
14
0
0
0
0
27
0
% T
% Val:
0
0
0
7
0
20
14
20
0
0
7
14
0
7
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _