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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTYMK
All Species:
34.85
Human Site:
S46
Identified Species:
54.76
UniProt:
P23919
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23919
NP_036277.2
212
23819
S46
L
L
R
F
P
E
R
S
T
E
I
G
K
L
L
Chimpanzee
Pan troglodytes
XP_001161682
169
19013
L26
K
S
T
Q
S
R
K
L
V
E
A
L
C
A
A
Rhesus Macaque
Macaca mulatta
XP_001094132
212
23926
S46
L
L
R
F
P
E
R
S
T
E
I
G
K
L
L
Dog
Lupus familis
XP_851996
156
17492
G20
S
A
R
V
P
G
L
G
Q
V
H
R
P
L
I
Cat
Felis silvestris
Mouse
Mus musculus
P97930
212
23896
S46
L
L
R
F
P
E
R
S
T
E
I
G
K
L
L
Rat
Rattus norvegicus
NP_001100395
212
23955
S46
L
L
R
F
P
E
R
S
T
E
I
G
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513078
670
74072
S503
L
N
K
Y
P
Q
R
S
T
E
I
G
K
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032187
212
24114
T46
I
M
R
F
P
D
R
T
T
K
I
G
Q
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611290
211
23800
S47
P
M
N
F
P
E
R
S
S
S
I
G
Q
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22018
218
24324
S57
L
Q
A
F
P
D
R
S
S
S
I
G
K
L
I
Sea Urchin
Strong. purpuratus
XP_784160
171
19446
E30
K
L
V
E
S
M
L
E
K
G
M
K
A
E
L
Poplar Tree
Populus trichocarpa
XP_002298600
222
24888
S58
L
W
R
F
P
D
R
S
T
S
V
G
Q
M
I
Maize
Zea mays
NP_001150303
255
27917
A93
G
W
S
F
P
D
R
A
T
S
V
G
Q
M
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001078772
271
30359
E107
L
W
R
F
P
D
R
E
T
S
V
G
Q
M
I
Baker's Yeast
Sacchar. cerevisiae
P00572
216
24669
T43
L
K
F
P
E
R
S
T
R
I
G
G
L
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.7
95.7
55.1
N.A.
81.1
81.1
N.A.
24.1
N.A.
N.A.
64.1
N.A.
44.8
N.A.
40.3
51.8
Protein Similarity:
100
79.7
98.5
64.1
N.A.
90.5
89.6
N.A.
29.1
N.A.
N.A.
83.9
N.A.
61.7
N.A.
64.2
65.5
P-Site Identity:
100
6.6
100
20
N.A.
100
100
N.A.
73.3
N.A.
N.A.
53.3
N.A.
46.6
N.A.
60
13.3
P-Site Similarity:
100
13.3
100
26.6
N.A.
100
100
N.A.
93.3
N.A.
N.A.
100
N.A.
80
N.A.
80
20
Percent
Protein Identity:
44.5
38
N.A.
38
43.9
N.A.
Protein Similarity:
67.5
53.3
N.A.
55.7
61.1
N.A.
P-Site Identity:
53.3
33.3
N.A.
46.6
13.3
N.A.
P-Site Similarity:
86.6
73.3
N.A.
80
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
7
0
0
7
0
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
7
34
0
14
0
40
0
0
0
7
0
% E
% Phe:
0
0
7
67
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
7
0
7
0
7
7
80
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
7
54
0
0
7
47
% I
% Lys:
14
7
7
0
0
0
7
0
7
7
0
7
40
0
0
% K
% Leu:
60
34
0
0
0
0
14
7
0
0
0
7
7
54
40
% L
% Met:
0
14
0
0
0
7
0
0
0
0
7
0
0
20
0
% M
% Asn:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
7
0
0
7
80
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
7
0
7
0
7
0
0
7
0
0
0
34
0
0
% Q
% Arg:
0
0
54
0
0
14
74
0
7
0
0
7
0
0
0
% R
% Ser:
7
7
7
0
14
0
7
54
14
34
0
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
14
60
0
0
0
0
0
0
% T
% Val:
0
0
7
7
0
0
0
0
7
7
20
0
0
7
0
% V
% Trp:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _