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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTYMK All Species: 28.48
Human Site: S54 Identified Species: 44.76
UniProt: P23919 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23919 NP_036277.2 212 23819 S54 T E I G K L L S S Y L Q K K S
Chimpanzee Pan troglodytes XP_001161682 169 19013 G34 V E A L C A A G H R A E L L R
Rhesus Macaque Macaca mulatta XP_001094132 212 23926 S54 T E I G K L L S S Y L E K K S
Dog Lupus familis XP_851996 156 17492 K28 Q V H R P L I K K K L S Q G I
Cat Felis silvestris
Mouse Mus musculus P97930 212 23896 N54 T E I G K L L N S Y L E K K T
Rat Rattus norvegicus NP_001100395 212 23955 S54 T E I G K L L S S Y L E K K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513078 670 74072 S511 T E I G K L L S S Y L E R K I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032187 212 24114 S54 T K I G Q L I S S Y L E K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611290 211 23800 N55 S S I G Q V I N S Y L T N S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22018 218 24324 D65 S S I G K L I D Q Y L R K E I
Sea Urchin Strong. purpuratus XP_784160 171 19446 M38 K G M K A E L M R F P E R S T
Poplar Tree Populus trichocarpa XP_002298600 222 24888 S66 T S V G Q M I S A Y L S N K S
Maize Zea mays NP_001150303 255 27917 S101 T S V G Q M I S S Y L A N D S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001078772 271 30359 S115 T S V G Q M I S A Y L S N K S
Baker's Yeast Sacchar. cerevisiae P00572 216 24669 E51 R I G G L I N E Y L T D D S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.7 95.7 55.1 N.A. 81.1 81.1 N.A. 24.1 N.A. N.A. 64.1 N.A. 44.8 N.A. 40.3 51.8
Protein Similarity: 100 79.7 98.5 64.1 N.A. 90.5 89.6 N.A. 29.1 N.A. N.A. 83.9 N.A. 61.7 N.A. 64.2 65.5
P-Site Identity: 100 6.6 93.3 13.3 N.A. 80 86.6 N.A. 80 N.A. N.A. 73.3 N.A. 33.3 N.A. 46.6 6.6
P-Site Similarity: 100 13.3 100 26.6 N.A. 100 100 N.A. 93.3 N.A. N.A. 100 N.A. 66.6 N.A. 73.3 40
Percent
Protein Identity: 44.5 38 N.A. 38 43.9 N.A.
Protein Similarity: 67.5 53.3 N.A. 55.7 61.1 N.A.
P-Site Identity: 46.6 46.6 N.A. 46.6 6.6 N.A.
P-Site Similarity: 80 73.3 N.A. 80 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 7 7 0 14 0 7 7 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 7 7 7 0 % D
% Glu: 0 40 0 0 0 7 0 7 0 0 0 47 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 0 7 7 80 0 0 0 7 0 0 0 0 0 7 0 % G
% His: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 54 0 0 7 47 0 0 0 0 0 0 0 20 % I
% Lys: 7 7 0 7 40 0 0 7 7 7 0 0 40 54 7 % K
% Leu: 0 0 0 7 7 54 40 0 0 7 80 0 7 7 0 % L
% Met: 0 0 7 0 0 20 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 14 0 0 0 0 27 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 7 0 0 0 34 0 0 0 7 0 0 7 7 0 0 % Q
% Arg: 7 0 0 7 0 0 0 0 7 7 0 7 14 0 7 % R
% Ser: 14 34 0 0 0 0 0 54 54 0 0 20 0 20 40 % S
% Thr: 60 0 0 0 0 0 0 0 0 0 7 7 0 0 20 % T
% Val: 7 7 20 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 74 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _