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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTYMK All Species: 41.21
Human Site: T21 Identified Species: 64.76
UniProt: P23919 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23919 NP_036277.2 212 23819 T21 V D R A G K S T Q S R K L V E
Chimpanzee Pan troglodytes XP_001161682 169 19013 L8 M A A R R G A L I V L E G V D
Rhesus Macaque Macaca mulatta XP_001094132 212 23926 T21 V D R A G K S T Q S R K L V E
Dog Lupus familis XP_851996 156 17492
Cat Felis silvestris
Mouse Mus musculus P97930 212 23896 T21 V D R A G K T T Q G L K L V T
Rat Rattus norvegicus NP_001100395 212 23955 T21 V D R A G K T T Q C L R L V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513078 670 74072 S325 N E V I M S A S G A C K L I D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032187 212 24114 T21 V D R A G K T T Q C Q K L V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611290 211 23800 T22 C D R S G K T T Q S R L L V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22018 218 24324 T23 L D R S G K S T Q A K R L V E
Sea Urchin Strong. purpuratus XP_784160 171 19446 D13 L V V F E G C D R S G K S T Q
Poplar Tree Populus trichocarpa XP_002298600 222 24888 S33 L D R S G K T S Q S S R L L S
Maize Zea mays NP_001150303 255 27917 S68 L D R S G K T S Q C A R L L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001078772 271 30359 T82 L D R S G K S T Q C A K L L S
Baker's Yeast Sacchar. cerevisiae P00572 216 24669 T20 L D R T G K T T Q C N I L Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.7 95.7 55.1 N.A. 81.1 81.1 N.A. 24.1 N.A. N.A. 64.1 N.A. 44.8 N.A. 40.3 51.8
Protein Similarity: 100 79.7 98.5 64.1 N.A. 90.5 89.6 N.A. 29.1 N.A. N.A. 83.9 N.A. 61.7 N.A. 64.2 65.5
P-Site Identity: 100 6.6 100 0 N.A. 73.3 66.6 N.A. 13.3 N.A. N.A. 73.3 N.A. 73.3 N.A. 66.6 13.3
P-Site Similarity: 100 33.3 100 0 N.A. 80 80 N.A. 53.3 N.A. N.A. 93.3 N.A. 86.6 N.A. 100 33.3
Percent
Protein Identity: 44.5 38 N.A. 38 43.9 N.A.
Protein Similarity: 67.5 53.3 N.A. 55.7 61.1 N.A.
P-Site Identity: 46.6 40 N.A. 60 46.6 N.A.
P-Site Similarity: 86.6 80 N.A. 80 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 34 0 0 14 0 0 14 14 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 7 0 0 34 7 0 0 0 0 % C
% Asp: 0 74 0 0 0 0 0 7 0 0 0 0 0 0 14 % D
% Glu: 0 7 0 0 7 0 0 0 0 0 0 7 0 0 27 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 74 14 0 0 7 7 7 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 7 0 0 7 0 7 0 % I
% Lys: 0 0 0 0 0 74 0 0 0 0 7 47 0 0 7 % K
% Leu: 40 0 0 0 0 0 0 7 0 0 20 7 80 20 0 % L
% Met: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 74 0 7 0 0 0 14 % Q
% Arg: 0 0 74 7 7 0 0 0 7 0 20 27 0 0 0 % R
% Ser: 0 0 0 34 0 7 27 20 0 34 7 0 7 0 20 % S
% Thr: 0 0 0 7 0 0 47 60 0 0 0 0 0 7 14 % T
% Val: 34 7 14 0 0 0 0 0 0 7 0 0 0 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _