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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTYMK All Species: 40.91
Human Site: T47 Identified Species: 64.29
UniProt: P23919 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23919 NP_036277.2 212 23819 T47 L R F P E R S T E I G K L L S
Chimpanzee Pan troglodytes XP_001161682 169 19013 V27 S T Q S R K L V E A L C A A G
Rhesus Macaque Macaca mulatta XP_001094132 212 23926 T47 L R F P E R S T E I G K L L S
Dog Lupus familis XP_851996 156 17492 Q21 A R V P G L G Q V H R P L I K
Cat Felis silvestris
Mouse Mus musculus P97930 212 23896 T47 L R F P E R S T E I G K L L N
Rat Rattus norvegicus NP_001100395 212 23955 T47 L R F P E R S T E I G K L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513078 670 74072 T504 N K Y P Q R S T E I G K L L S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032187 212 24114 T47 M R F P D R T T K I G Q L I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611290 211 23800 S48 M N F P E R S S S I G Q V I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22018 218 24324 S58 Q A F P D R S S S I G K L I D
Sea Urchin Strong. purpuratus XP_784160 171 19446 K31 L V E S M L E K G M K A E L M
Poplar Tree Populus trichocarpa XP_002298600 222 24888 T59 W R F P D R S T S V G Q M I S
Maize Zea mays NP_001150303 255 27917 T94 W S F P D R A T S V G Q M I S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001078772 271 30359 T108 W R F P D R E T S V G Q M I S
Baker's Yeast Sacchar. cerevisiae P00572 216 24669 R44 K F P E R S T R I G G L I N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.7 95.7 55.1 N.A. 81.1 81.1 N.A. 24.1 N.A. N.A. 64.1 N.A. 44.8 N.A. 40.3 51.8
Protein Similarity: 100 79.7 98.5 64.1 N.A. 90.5 89.6 N.A. 29.1 N.A. N.A. 83.9 N.A. 61.7 N.A. 64.2 65.5
P-Site Identity: 100 6.6 100 20 N.A. 93.3 100 N.A. 73.3 N.A. N.A. 60 N.A. 46.6 N.A. 53.3 13.3
P-Site Similarity: 100 13.3 100 26.6 N.A. 100 100 N.A. 93.3 N.A. N.A. 100 N.A. 86.6 N.A. 73.3 20
Percent
Protein Identity: 44.5 38 N.A. 38 43.9 N.A.
Protein Similarity: 67.5 53.3 N.A. 55.7 61.1 N.A.
P-Site Identity: 53.3 40 N.A. 46.6 6.6 N.A.
P-Site Similarity: 86.6 80 N.A. 80 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 7 0 0 7 0 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 7 7 34 0 14 0 40 0 0 0 7 0 7 % E
% Phe: 0 7 67 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 7 0 7 7 80 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 54 0 0 7 47 0 % I
% Lys: 7 7 0 0 0 7 0 7 7 0 7 40 0 0 7 % K
% Leu: 34 0 0 0 0 14 7 0 0 0 7 7 54 40 0 % L
% Met: 14 0 0 0 7 0 0 0 0 7 0 0 20 0 7 % M
% Asn: 7 7 0 0 0 0 0 0 0 0 0 0 0 7 14 % N
% Pro: 0 0 7 80 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 7 0 7 0 7 0 0 7 0 0 0 34 0 0 0 % Q
% Arg: 0 54 0 0 14 74 0 7 0 0 7 0 0 0 0 % R
% Ser: 7 7 0 14 0 7 54 14 34 0 0 0 0 0 54 % S
% Thr: 0 7 0 0 0 0 14 60 0 0 0 0 0 0 0 % T
% Val: 0 7 7 0 0 0 0 7 7 20 0 0 7 0 0 % V
% Trp: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _