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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FSHR All Species: 10.3
Human Site: T568 Identified Species: 28.33
UniProt: P23945 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23945 NP_000136.2 695 78295 T568 I V S S S S D T R I A K R M A
Chimpanzee Pan troglodytes XP_525753 695 78196 T568 I V S S S S D T R I A K R M A
Rhesus Macaque Macaca mulatta XP_001114171 695 78240 T568 I V S S S S D T R I A K R M A
Dog Lupus familis XP_538488 692 78161 S565 N P N I V S S S S D T K I A K
Cat Felis silvestris
Mouse Mus musculus P35378 692 77751 D566 N I V S S S R D T K I A K R M
Rat Rattus norvegicus P20395 692 77663 D566 T I V S S S S D T K I A K R M
Wallaby Macropus eugenll Q6YNB6 694 78462 D568 N I I S S T S D A K I A K R M
Platypus Ornith. anatinus
Chicken Gallus gallus P79763 693 78680 D567 N V I S S N S D T K I A K R M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001001812 668 75168 F542 L T V R N P A F V P A N A D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.8 91.3 N.A. 87.7 89.6 81.2 N.A. 73.2 N.A. 53.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 98.2 95.8 N.A. 92.6 93.9 89 N.A. 83.4 N.A. 71.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 20 20 13.3 N.A. 20 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 33.3 33.3 33.3 N.A. 33.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 0 12 0 45 45 12 12 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 34 45 0 12 0 0 0 12 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 34 34 23 12 0 0 0 0 0 34 45 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 45 0 45 45 0 12 % K
% Leu: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 56 % M
% Asn: 45 0 12 0 12 12 0 0 0 0 0 12 0 0 0 % N
% Pro: 0 12 0 0 0 12 0 0 0 12 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 0 0 12 0 34 0 0 0 34 45 0 % R
% Ser: 0 0 34 78 78 67 45 12 12 0 0 0 0 0 0 % S
% Thr: 12 12 0 0 0 12 0 34 34 0 12 0 0 0 0 % T
% Val: 0 45 34 0 12 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _