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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A2
All Species:
33.64
Human Site:
Y294
Identified Species:
67.27
UniProt:
P23975
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23975
NP_001034.1
617
69332
Y294
A
S
N
G
I
N
A
Y
L
H
I
D
F
Y
R
Chimpanzee
Pan troglodytes
XP_001167680
617
69344
Y294
A
S
N
G
I
N
A
Y
L
H
I
D
F
Y
R
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
Y312
A
W
R
G
V
L
F
Y
L
K
P
N
W
Q
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55192
617
69144
Y294
A
S
N
G
I
N
A
Y
L
H
I
D
F
Y
R
Rat
Rattus norvegicus
P23977
619
68728
Y296
A
M
D
G
I
R
A
Y
L
S
V
D
F
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508462
865
94609
Y542
A
Y
N
G
I
N
A
Y
L
H
I
D
F
G
R
Chicken
Gallus gallus
NP_990047
635
71560
Y312
A
Y
N
G
I
N
A
Y
L
H
I
D
F
R
R
Frog
Xenopus laevis
A7Y2X0
790
87434
F446
A
G
D
G
I
W
W
F
I
M
P
K
W
E
K
Zebra Danio
Brachydanio rerio
XP_694138
678
75838
Y302
A
M
N
G
I
R
A
Y
L
H
I
D
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51905
622
69307
Y304
A
D
E
G
I
K
Y
Y
L
T
P
E
W
H
K
Honey Bee
Apis mellifera
NP_001139210
643
71921
Y281
S
L
E
G
I
R
Y
Y
L
N
P
N
F
S
A
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
Y290
W
Q
N
G
I
E
Y
Y
L
R
P
N
F
E
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
49
N.A.
N.A.
94.1
66.7
N.A.
63.3
83.1
35.5
64.7
N.A.
49.2
52.2
47.4
N.A.
Protein Similarity:
100
99.6
67.1
N.A.
N.A.
97.2
79.9
N.A.
67.6
88.8
53.5
75.5
N.A.
69.2
69.9
65.9
N.A.
P-Site Identity:
100
100
26.6
N.A.
N.A.
100
66.6
N.A.
86.6
86.6
20
66.6
N.A.
33.3
33.3
40
N.A.
P-Site Similarity:
100
100
53.3
N.A.
N.A.
100
80
N.A.
86.6
86.6
53.3
73.3
N.A.
60
53.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
84
0
0
0
0
0
59
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
0
0
0
59
0
0
0
% D
% Glu:
0
0
17
0
0
9
0
0
0
0
0
9
0
17
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
67
0
0
% F
% Gly:
0
9
0
100
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
9
0
% H
% Ile:
0
0
0
0
92
0
0
0
9
0
50
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
9
0
9
0
9
34
% K
% Leu:
0
9
0
0
0
9
0
0
92
0
0
0
9
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
59
0
0
42
0
0
0
9
0
25
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
9
0
0
25
0
0
0
9
0
0
0
9
50
% R
% Ser:
9
25
0
0
0
0
0
0
0
9
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
9
9
0
0
0
9
9
0
0
0
0
0
25
0
0
% W
% Tyr:
0
17
0
0
0
0
25
92
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _