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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPT
All Species:
19.09
Human Site:
T178
Identified Species:
42
UniProt:
P24298
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24298
NP_005300.1
496
54637
T178
L
V
A
G
E
G
H
T
R
T
G
V
L
I
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093616
496
54621
T178
L
V
A
G
E
G
H
T
R
T
G
V
L
I
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR5
496
55124
A178
L
V
A
G
E
G
R
A
R
T
G
V
L
I
P
Rat
Rattus norvegicus
P25409
496
55091
A178
L
V
S
G
E
G
R
A
R
T
G
V
L
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414111
644
70325
S326
L
V
S
G
G
G
K
S
R
T
G
V
M
I
P
Frog
Xenopus laevis
Q6GM82
540
59778
S222
L
V
S
G
Q
G
K
S
R
T
G
V
M
I
P
Zebra Danio
Brachydanio rerio
Q6NYL5
549
61074
T231
L
T
A
G
E
G
L
T
R
T
G
V
M
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727696
575
64028
K258
I
N
A
E
V
G
C
K
A
P
G
V
M
V
P
Honey Bee
Apis mellifera
XP_392720
543
60811
K226
F
N
E
K
I
D
G
K
P
S
G
V
M
I
P
Nematode Worm
Caenorhab. elegans
NP_001021021
504
55782
K187
F
I
N
H
N
N
A
K
K
V
G
V
M
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P52892
507
56751
S188
L
S
L
L
C
K
D
S
Q
T
G
L
L
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
N.A.
N.A.
87.3
87.9
N.A.
N.A.
52.9
66.6
63.3
N.A.
46.6
54.1
54.5
N.A.
Protein Similarity:
100
N.A.
98.7
N.A.
N.A.
92.5
93.3
N.A.
N.A.
65.9
79.8
77
N.A.
63.1
67.7
70.2
N.A.
P-Site Identity:
100
N.A.
100
N.A.
N.A.
86.6
80
N.A.
N.A.
66.6
66.6
73.3
N.A.
33.3
26.6
26.6
N.A.
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
86.6
93.3
80
N.A.
53.3
40
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
61.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
46
0
0
0
10
19
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
46
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
64
10
73
10
0
0
0
100
0
0
0
0
% G
% His:
0
0
0
10
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
0
0
0
0
0
0
0
91
0
% I
% Lys:
0
0
0
10
0
10
19
28
10
0
0
0
0
0
0
% K
% Leu:
73
0
10
10
0
0
10
0
0
0
0
10
46
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% M
% Asn:
0
19
10
0
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
91
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
19
0
64
0
0
0
0
0
0
% R
% Ser:
0
10
28
0
0
0
0
28
0
10
0
0
0
0
10
% S
% Thr:
0
10
0
0
0
0
0
28
0
73
0
0
0
0
0
% T
% Val:
0
55
0
0
10
0
0
0
0
10
0
91
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _