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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP11
All Species:
14.24
Human Site:
T268
Identified Species:
34.81
UniProt:
P24347
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24347
NP_005931.2
488
54618
T268
W
P
T
V
T
S
R
T
P
A
L
G
P
Q
A
Chimpanzee
Pan troglodytes
XP_515022
469
52600
T249
W
P
T
V
T
S
R
T
P
A
L
G
P
Q
A
Rhesus Macaque
Macaca mulatta
XP_001083910
488
54748
T268
R
P
T
V
T
S
R
T
P
A
L
G
P
Q
A
Dog
Lupus familis
XP_543534
489
54823
P269
R
T
A
P
T
S
R
P
P
A
V
G
P
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q02853
492
55423
A272
Q
M
A
P
T
S
P
A
P
T
L
S
S
Q
A
Rat
Rattus norvegicus
Q499S5
491
55493
T271
Q
L
T
P
T
S
P
T
P
T
L
S
S
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232777
502
56708
P280
K
L
D
P
D
P
T
P
T
Q
P
A
E
L
P
Frog
Xenopus laevis
Q11005
477
54423
T256
R
P
P
T
P
S
P
T
P
R
V
E
V
N
Q
Zebra Danio
Brachydanio rerio
XP_692205
483
55535
P277
V
R
A
Q
P
Q
I
P
A
E
T
N
D
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780356
489
56331
S250
S
I
Y
G
I
N
S
S
P
R
P
G
D
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
97.3
86.9
N.A.
81.7
81.6
N.A.
N.A.
64.3
61.4
56.3
N.A.
N.A.
N.A.
N.A.
39.8
Protein Similarity:
100
93.4
97.7
91.4
N.A.
87.4
86.7
N.A.
N.A.
73.9
73.9
67.4
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
93.3
60
N.A.
40
53.3
N.A.
N.A.
0
26.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
66.6
N.A.
40
53.3
N.A.
N.A.
0
33.3
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
0
0
0
10
10
40
0
10
0
0
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
20
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
0
0
0
0
0
0
0
50
0
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
40
10
40
20
10
30
30
80
0
20
0
40
0
20
% P
% Gln:
20
0
0
10
0
10
0
0
0
10
0
0
0
60
10
% Q
% Arg:
30
10
0
0
0
0
40
0
0
20
0
0
0
10
0
% R
% Ser:
10
0
0
0
0
70
10
10
0
0
0
20
20
0
0
% S
% Thr:
0
10
40
10
60
0
10
50
10
20
10
0
0
0
0
% T
% Val:
10
0
0
30
0
0
0
0
0
0
20
0
10
0
0
% V
% Trp:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _